A dynamic growth model of Dunaliella salina: parameter identification and profile likelihood analysis.
Bioresour Technol
; 173: 21-31, 2014 Dec.
Article
en En
| MEDLINE
| ID: mdl-25280110
In this work, a photoautotrophic growth model incorporating light and nutrient effects on growth and pigmentation of Dunaliella salina was formulated. The model equations were taken from literature and modified according to the experimental setup with special emphasis on model reduction. The proposed model has been evaluated with experimental data of D. salina cultivated in a flat-plate photobioreactor under stressed and non-stressed conditions. Simulation results show that the model can represent the experimental data accurately. The identifiability of the model parameters was studied using the profile likelihood method. This analysis revealed that three model parameters are practically non-identifiable. However, some of these non-identifiabilities can be resolved by model reduction and additional measurements. As a conclusion, our results suggest that the proposed model equations result in a predictive growth model for D. salina.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fotosíntesis
/
Reactores Biológicos
/
Proliferación Celular
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Chlorophyta
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Modelos Biológicos
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Bioresour Technol
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2014
Tipo del documento:
Article
País de afiliación:
Alemania
Pais de publicación:
Reino Unido