Vizantin inhibits endotoxin-mediated immune responses via the TLR 4/MD-2 complex.

Oda, Masataka; Yamamoto, Hirofumi; Shibutani, Masahiro; Nakano, Mayo; Yabiku, Kenta; Tarui, Takafumi; Kameyama, Naoya; Shirakawa, Daiki; Obayashi, Sumiyo; Watanabe, Naoyuki; Nakase, Hiroshi; Suenaga, Midori; Matsunaga, Yoichi; Nagahama, Masahiro; Takahashi, Hironobu; Imagawa, Hiroshi; Kurosawa, Mie; Terao, Yutaka; Nishizawa, Mugio; Sakurai, Jun

Oda, Masataka; Yamamoto, Hirofumi; Shibutani, Masahiro; Nakano, Mayo; Yabiku, Kenta; Tarui, Takafumi; Kameyama, Naoya; Shirakawa, Daiki; Obayashi, Sumiyo; Watanabe, Naoyuki; Nakase, Hiroshi; Suenaga, Midori; Matsunaga, Yoichi; Nagahama, Masahiro; Takahashi, Hironobu; Imagawa, Hiroshi; Kurosawa, Mie; Terao, Yutaka; Nishizawa, Mugio; Sakurai, Jun.

Afiliación

Oda M; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan; Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, 2-5274, Gakkocho-dori, Chuo-ku, Niigata 951-8514,
Yamamoto H; Department of Chemistry and Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Shibutani M; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Nakano M; Department of Chemistry and Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Yabiku K; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Tarui T; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Kameyama N; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Shirakawa D; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Obayashi S; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Watanabe N; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Nakase H; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Suenaga M; Department of Medical Pharmacology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan; and.
Matsunaga Y; Department of Medical Pharmacology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan; and.
Nagahama M; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Takahashi H; Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Imagawa H; Department of Chemistry and Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Kurosawa M; Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, 2-5274, Gakkocho-dori, Chuo-ku, Niigata 951-8514, Japan;
Terao Y; Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, 2-5274, Gakkocho-dori, Chuo-ku, Niigata 951-8514, Japan;
Nishizawa M; Department of Chemistry and Functional Molecule, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan;
Sakurai J; Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan; sakurai@ph.bunri-u.ac.jp.

J Immunol ; 193(9): 4507-14, 2014 Nov 01.

Article en En | MEDLINE | ID: mdl-25261480

Asunto(s)

Endotoxinas/inmunología; Glucolípidos/farmacología; Inmunidad/efectos de los fármacos; Antígeno 96 de los Linfocitos/metabolismo; Trehalosa/análogos & derivados; Animales; Quimiocina CCL4/biosíntesis; Citocinas/biosíntesis; Expresión Génica; Glucolípidos/metabolismo; Células HEK293; Humanos; Inmunidad/genética; Mediadores de Inflamación/metabolismo; Lipopolisacáridos/inmunología; Lipopolisacáridos/farmacología; Antígeno 96 de los Linfocitos/química; Antígeno 96 de los Linfocitos/genética; Macrófagos/química; Macrófagos/efectos de los fármacos; Macrófagos/inmunología; Macrófagos/metabolismo; Ratones; Ratones Noqueados; Modelos Moleculares; Unión Proteica; Conformación Proteica; Transporte de Proteínas; Receptor Toll-Like 4/genética; Receptor Toll-Like 4/metabolismo; Trehalosa/metabolismo; Trehalosa/farmacología

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trehalosa / Glucolípidos / Endotoxinas / Antígeno 96 de los Linfocitos / Inmunidad Límite: Animals / Humans Idioma: En Revista: J Immunol Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos

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