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Anti-Müllerian hormone levels in the follicular fluid of the preovulatory follicle: a predictor for oocyte fertilization and quality of embryo.
Kim, Jee Hyun; Lee, Jung Ryeol; Chang, Hye Jin; Jee, Byung Chul; Suh, Chang Suk; Kim, Seok Hyun.
Afiliación
  • Kim JH; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
  • Lee JR; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
  • Chang HJ; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea. ; Health Promotion Center, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Jee BC; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
  • Suh CS; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
  • Kim SH; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
J Korean Med Sci ; 29(9): 1266-70, 2014 Sep.
Article en En | MEDLINE | ID: mdl-25246746
This prospective study investigated the relationship between anti-Müllerian hormone (AMH) level in the follicular fluid (FF) and the quality of the oocyte and embryo. A total of 65 FF samples from 54 women were included in this study. FF was collected from the largest preovulatory follicle sized≥20 mm of mean diameter from each ovary. Samples were divided into 3 groups according to the FF AMH levels: below the 33th percentile (low group, FF AMH<2.1 ng/mL, n=21), between the 33th and the 67th percentile (intermediate group, FF AMH=2.1-3.6 ng/mL, n=22), and above the 67th percentile (high group, FF AMH>3.6 ng/mL, n=22). The quality of the ensuing oocytes and embryos was evaluated by fertilization rate and embryo score. FF AMH levels correlated positively with the matched embryo score on day 3 after fertilization (r=0.331, P=0.015). The normal fertilization rate was significantly lower in the low group than in the intermediate group (61.9% vs. 95.5% vs. 77.3%, respectively, P=0.028). Our results suggest that the FF AMH level could be a predictor of the ensuing oocyte and embryo quality.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Líquido Folicular / Embrión de Mamíferos / Hormona Antimülleriana Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans Idioma: En Revista: J Korean Med Sci Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article Pais de publicación: Corea del Sur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Líquido Folicular / Embrión de Mamíferos / Hormona Antimülleriana Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans Idioma: En Revista: J Korean Med Sci Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article Pais de publicación: Corea del Sur