How do high- and low-frequency repetitive transcranial magnetic stimulations modulate the temporal cortex.
Psychophysiology
; 52(2): 192-8, 2015 Feb.
Article
en En
| MEDLINE
| ID: mdl-25223883
Few studies have examined the impact of repetitive transcranial magnetic stimulation (rTMS) on the cortical excitability of nonmotor cortices; current treatments often target the temporal or prefrontal cortex. We used auditory evoked potentials recorded in 24 healthy subjects to evaluate the neuromodulatory effects of low- and high-frequency rTMS in the temporal lobe. Both auditory evoked potential P50 amplitude, a marker of cortical excitability, and P50 ratio, a marker of sensory gating known to be impaired in patients with auditory verbal hallucinations, were compared before and after rTMS. We observed a similar effect after both stimulation frequencies, with a decrease in P50 amplitude and no significant effect on P50 ratio. Low- and high-frequency rTMS applied to the temporal lobe seemed to exert the same cortical neuromodulation effect, while auditory sensory gating may not be modulated by temporal rTMS.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lóbulo Temporal
/
Estimulación Magnética Transcraneal
/
Potenciales Evocados Auditivos
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Psychophysiology
Año:
2015
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Estados Unidos