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Depression and executive dysfunction contribute to a metamemory deficit among individuals with methamphetamine use disorders.
Casaletto, K B; Obermeit, L; Morgan, E E; Weber, E; Franklin, D R; Grant, I; Woods, S P.
Afiliación
  • Casaletto KB; SDSU/UCSD Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
  • Obermeit L; SDSU/UCSD Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
  • Morgan EE; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
  • Weber E; SDSU/UCSD Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
  • Franklin DR; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
  • Grant I; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
  • Woods SP; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Addict Behav ; 40: 45-50, 2015 Jan.
Article en En | MEDLINE | ID: mdl-25222847
OBJECTIVE: Chronic methamphetamine (MA) use is associated with moderate deficits in learning and memory, but the extend to which MA users are aware of such memory deficits (i.e., metamemory) is not known. METHODS: In the current study, 195 participants with lifetime MA use diagnoses (MA +) and 195 non-MA-using comparison subjects (MA -) underwent comprehensive neuropsychiatry research assessments, including performance-based and self-report measures of episodic memory. RESULTS: MA use disorders, major depressive disorder (MDD), and their interaction were uniquely associated with metamemory functioning, such that MDD increased the likelihood of a metamemory deficit among MA + participants. Within the MA group, individuals who over-estimated their memory abilities demonstrated greater executive dysfunction and lower cognitive reserve. CONCLUSIONS: Chronic MA use is associated with reduced awareness of objective deficits in memory acquisition and recall, which is particularly exacerbated by the presence of major depression. Efforts to enhance metamemory accuracy and deployment of compensatory mnemonic strategies may benefit substance abuse treatment outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Conocimiento / Trastornos Relacionados con Anfetaminas / Trastorno Depresivo Mayor / Función Ejecutiva / Trastornos de la Memoria / Metanfetamina Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Addict Behav Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Conocimiento / Trastornos Relacionados con Anfetaminas / Trastorno Depresivo Mayor / Función Ejecutiva / Trastornos de la Memoria / Metanfetamina Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Addict Behav Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido