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Shear wave elastography: a new noninvasive tool to assess the intensity of fibrosis of irradiated salivary glands in head and neck cancer patients.
Kaluzny, Jaroslaw; Kopec, Tomasz; Szczepanek-Parulska, Ewelina; Stangierski, Adam; Gurgul, Edyta; Ruchala, Marek; Milecki, Piotr; Wierzbicka, Malgorzata.
Afiliación
  • Kaluzny J; Department of Otolaryngology, Head and Neck Surgery, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland.
  • Kopec T; Department of Otolaryngology, Head and Neck Surgery, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland.
  • Szczepanek-Parulska E; Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland.
  • Stangierski A; Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland.
  • Gurgul E; Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland.
  • Ruchala M; Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland.
  • Milecki P; Great Poland Oncology Center, Department of Electroradiology, Poznan University of Medical Sciences, 15 Garbary Street, 61-866 Poznan, Poland.
  • Wierzbicka M; Department of Otolaryngology, Head and Neck Surgery, Poznan University of Medical Sciences, 49 Przybyszewskiego Street, 60-355 Poznan, Poland.
Biomed Res Int ; 2014: 157809, 2014.
Article en En | MEDLINE | ID: mdl-25202703
The aim of the study was to assess salivary gland parenchyma by means of sonoelastography in patients irradiated for head and neck squamous cell carcinoma (HNSCC). The studied group consisted of 52 patients after radiotherapy (RT) and 54 healthy volunteers. All of the former were treated for advanced larynx (40), oropharynx (9), or maxilla (3) squamous cancers and suffered from chronic dryness. Ultrasonography (US) and elastography (ES) were performed, as well as an assessment of the amount of saliva and Common Terminology Criteria for Adverse Events (CTCAE) scale. There was a statistical difference between ES values in the RT group and in the controls for parotid glands (41.7 kPa versus 26.03 kPa, P = 0.0018) and for submandibular glands (37.6 kPa versus 22.4 kPa; P = 0.005). There was a significant correlation between the CTCAE scores and objective saliva amount (P = 0.0005), and the median amount of saliva in the examined group was lower than in the reference group (1.86 g versus 2.75 g, P = 0.0006). In conclusion sonoelastography adds a new parameter to ultrasonography in "one touch examination" and may be a useful tool for major salivary gland evaluation during the radiotherapy course and follow-up period.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glándulas Salivales / Resistencia al Corte / Diagnóstico por Imagen de Elasticidad / Neoplasias de Cabeza y Cuello Tipo de estudio: Diagnostic_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Biomed Res Int Año: 2014 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glándulas Salivales / Resistencia al Corte / Diagnóstico por Imagen de Elasticidad / Neoplasias de Cabeza y Cuello Tipo de estudio: Diagnostic_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Biomed Res Int Año: 2014 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos