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Serum uric acid levels in Chagas' disease.
Abreu, M C; Guimarães, R C; Krieger, H.
Afiliación
  • Abreu MC; Instituto Oswaldo Cruz, Departamento de Genética, Rio de Janeiro, Brasil.
Mem Inst Oswaldo Cruz ; 84(2): 151-5, 1989.
Article en En | MEDLINE | ID: mdl-2517563
Uricemia was studied in a sample of 192 individuals from a highly endemic site for Chagas' disease (Bambuí, State of Minas Gerais, Brazil). The sample had 50 serologically negative individuals (controls) and the positive ones were classified on the basis of the presence of electrocardiographic alterations (63), altered esophageal emptying (16), or without any sign on symptom of the disease (76). Only the individuals with the digestive form of chronic Chagas' disease showed hyperuricemia, when compared with the appropriate controls. Family data suggest that hyperuricemia is an effect of the digestive pathology, rather than a cause, since the non-infected sibs of the megaesophagous patients did not show elevated levels of serum uric acid. Possible mechanisms responsible for these findings are postulated.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Úrico / Enfermedad de Chagas Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Male Idioma: En Revista: Mem Inst Oswaldo Cruz Año: 1989 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Úrico / Enfermedad de Chagas Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Male Idioma: En Revista: Mem Inst Oswaldo Cruz Año: 1989 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil