In vivo 14C isotopic evaluation of amino acid oxidative catabolism in the growing chick. II. Slow respiratory 14CO2 and protein renewal.

Simonnet, F; Ng, L T; Auliac, P; Jacob, A; Pascaud, M

Simonnet, F; Ng, L T; Auliac, P; Jacob, A; Pascaud, M.

Afiliación

Simonnet F; Institut National des Science et Techniques Nucléaires, CEN Saclay, Gif-sur-Yvette, France.

Ann Nutr Metab ; 33(5): 279-83, 1989.

Article en En | MEDLINE | ID: mdl-2516428

RESUMEN

Analysis of the respiratory 14CO2 of growing chicks injected intraperitoneally with [1-14C] or [U-14C]glycine or valine has shown the presence of a delayed 'slow 14CO2' exponential component. The half-lives, about 3 h, are independent of the nature of the amino acid and of the age (1-3 weeks) of the animal. As supported by investigations in cycloheximide-treated chicks of the oxidative catabolism of glycine, valine and acetate, slow 14CO2 is significantly associated with the degradation of short-lived proteins.

Asunto(s)

Aminoácidos/metabolismo; Proteínas/metabolismo; Respiración; Acetatos/metabolismo; Animales; Animales Recién Nacidos; Dióxido de Carbono; Radioisótopos de Carbono; Pollos; Cicloheximida/farmacología; Glicina/metabolismo; Metionina/metabolismo; Oxidación-Reducción; Valina/metabolismo

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Respiración / Proteínas / Aminoácidos Límite: Animals Idioma: En Revista: Ann Nutr Metab Año: 1989 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Suiza

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