Frontal-temporal synchronization of EEG signals quantified by order patterns cross recurrence analysis during propofol anesthesia.
IEEE Trans Neural Syst Rehabil Eng
; 23(3): 468-74, 2015 May.
Article
en En
| MEDLINE
| ID: mdl-25163065
Characterizing brain dynamics during anesthesia is a main current challenge in anesthesia study. Several single channel electroencephalogram (EEG)-based commercial monitors like the Bispectral index (BIS) have suggested to examine EEG signal. But, the BIS index has obtained numerous critiques. In this study, we evaluate the concentration-dependent effect of the propofol on long-range frontal-temporal synchronization of EEG signals collected from eight subjects during a controlled induction and recovery design. We used order patterns cross recurrence plot and provide an index named order pattern laminarity (OPL) to assess changes in neuronal synchronization as the mechanism forming the foundation of conscious perception. The prediction probability of 0.9 and 0.84 for OPL and BIS specified that the OPL index correlated more strongly with effect-site propofol concentration. Also, our new index makes faster reaction to transients in EEG recordings based on pharmacokinetic and pharmacodynamic model parameters and demonstrates less variability at the point of loss of consciousness (standard deviation of 0.04 for OPL compared with 0.09 for BIS index). The result show that the OPL index can estimate anesthetic state of patient more efficiently than the BIS index in lightly sedated state with more tolerant of artifacts.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Propofol
/
Anestésicos Intravenosos
/
Sincronización de Fase en Electroencefalografía
/
Anestesia
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
IEEE Trans Neural Syst Rehabil Eng
Asunto de la revista:
ENGENHARIA BIOMEDICA
/
REABILITACAO
Año:
2015
Tipo del documento:
Article
Pais de publicación:
Estados Unidos