Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor &#945;: a contributor to endothelial cell glycocalyx dysfunction.

Ramnath, Raina; Foster, Rebecca R; Qiu, Yan; Cope, George; Butler, Matthew J; Salmon, Andrew H; Mathieson, Peter W; Coward, Richard J; Welsh, Gavin I; Satchell, Simon C

Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction.

Ramnath, Raina; Foster, Rebecca R; Qiu, Yan; Cope, George; Butler, Matthew J; Salmon, Andrew H; Mathieson, Peter W; Coward, Richard J; Welsh, Gavin I; Satchell, Simon C.

Afiliación

Ramnath R; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Foster RR; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Qiu Y; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Cope G; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Butler MJ; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Salmon AH; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Mathieson PW; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Coward RJ; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Welsh GI; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Satchell SC; Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, UK s.c.satchell@bristol.ac.uk.

FASEB J ; 28(11): 4686-99, 2014 Nov.

Article en En | MEDLINE | ID: mdl-25122554

Asunto(s)

Glicocálix/metabolismo; Metaloproteinasa 9 de la Matriz/metabolismo; Sindecano-4/metabolismo; Factor de Necrosis Tumoral alfa/farmacología; Membrana Celular; Células Cultivadas; Células Endoteliales/efectos de los fármacos; Células Endoteliales/metabolismo; Expresión Génica/fisiología; Técnicas de Silenciamiento del Gen; Humanos; Metaloproteinasa 9 de la Matriz/genética; Proteoglicanos/metabolismo

Palabras clave

heparan sulfate; microvascular permeability

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Necrosis Tumoral alfa / Glicocálix / Metaloproteinasa 9 de la Matriz / Sindecano-4 Límite: Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

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