High-pitch computed tomography pulmonary angiography with iterative reconstruction at 80 kVp and 20 mL contrast agent volume.
Eur Radiol
; 24(12): 3260-8, 2014 Dec.
Article
en En
| MEDLINE
| ID: mdl-25100336
OBJECTIVES: To evaluate the image quality, radiation dose and diagnostic accuracy of 80kVp, high-pitch CT pulmonary angiography (CTPA) with iterative reconstruction using 20 ml of contrast agent. METHODS: One hundred patients with suspected pulmonary embolism (PE) were randomly divided into two groups (n = 50 each; group A, 100 kVp, 1.2 pitch, 60 ml of contrast medium and filtered back projection algorithm; group B, 80 kVp, 2.2 pitch, 20 ml of contrast medium and sinogram affirmed iterative reconstruction). Image quality, diagnostic accuracy and radiation dose were evaluated and compared. RESULTS: Mean CT numbers of pulmonary arteries in group B were higher than those in group A (all P < 0.001). Contrast-to-noise ratio and signal-to-noise ratio of group B were higher than those of group A (both P < 0.001). There was no significant difference in subjective image quality scores between two groups (P = 0.807). The interobserver agreement was excellent (k = 0.836). There was no significant difference in diagnostic accuracy between the two groups (P > 0.05). Compared with group A, radiation dose of group B was reduced by 50.3% (P < 0.001). CONCLUSIONS: High-pitch CTPA at 80 kVp can obtain sufficient image quality in normal-weight individuals with 20 ml of contrast agent and half the radiation dose of a conventional CTPA protocol. KEY POINTS: CTPA is feasible at 80 kVp using only 20 ml of contrast agent. High-pitch CTPA at 80 kVp has an effective dose under 1 mSv. This CTPA protocol can obtain sufficient image quality in normal-weight individuals.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Arteria Pulmonar
/
Embolia Pulmonar
/
Procesamiento de Imagen Asistido por Computador
/
Angiografía
/
Tomografía Computarizada por Rayos X
/
Medios de Contraste
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2014
Tipo del documento:
Article
Pais de publicación:
Alemania