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The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions.
Orta, Manuel Luis; Höglund, Andreas; Calderón-Montaño, José Manuel; Domínguez, Inmaculada; Burgos-Morón, Estefanía; Visnes, Torkild; Pastor, Nuria; Ström, Cecilia; López-lázaro, Miguel; Helleday, Thomas.
Afiliación
  • Orta ML; Department of Cell Biology, Faculty of Biology, University of Seville, Avda. Reina Mercedes 6, 41012 Seville, Spain Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Swede
  • Höglund A; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden.
  • Calderón-Montaño JM; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden Department of Pharmacology, Faculty of Pharmacy, University of Seville, c/Professor García González, No. 2, 41012
  • Domínguez I; Department of Cell Biology, Faculty of Biology, University of Seville, Avda. Reina Mercedes 6, 41012 Seville, Spain.
  • Burgos-Morón E; Department of Pharmacology, Faculty of Pharmacy, University of Seville, c/Professor García González, No. 2, 41012 Seville, Spain.
  • Visnes T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden.
  • Pastor N; Department of Cell Biology, Faculty of Biology, University of Seville, Avda. Reina Mercedes 6, 41012 Seville, Spain.
  • Ström C; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden.
  • López-lázaro M; Department of Pharmacology, Faculty of Pharmacy, University of Seville, c/Professor García González, No. 2, 41012 Seville, Spain.
  • Helleday T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden thomas.helleday@scilifelab.se.
Nucleic Acids Res ; 42(14): 9108-20, 2014 Aug.
Article en En | MEDLINE | ID: mdl-25074383
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ftalazinas / Piperazinas / Azacitidina / Reparación del ADN / Inhibidores Enzimáticos / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Antimetabolitos Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ftalazinas / Piperazinas / Azacitidina / Reparación del ADN / Inhibidores Enzimáticos / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Antimetabolitos Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido