Nerve growth factor promotes expression of novel genes in intervertebral disc cells that regulate tissue degradation: Laboratory investigation.
J Neurosurg Spine
; 21(4): 653-61, 2014 Oct.
Article
en En
| MEDLINE
| ID: mdl-25062286
Palabras clave
AF = annulus fibrosus; BSA = bovine serum albumin; Chi3l1 = chitinase 3-like 1; EPK1/2 = extracellular-regulation kinase 1/2; HRP = horseradish peroxidase; IL-1ß = interleukin-1ß; IVD = intervertebral disc; LBP = low-back pain; Lcn2 = lipocalin 2; MAPK = mitogen-activated protein kinase; MMP3; Mmp3 = matrix metalloproteinase3; NF-κB = neurotrophic factor κB; NGF = nerve growth factor; NGFR = nerve growth factor receptor; NP = nucleus pulposus; PBS = phosphate-buffered saline; TBST = Tris-buffered saline/Tween; VE = vertebral endplate; chitinase 3-like 1; intervertebral disc degeneration; lipocalin 2; nerve growth factor; p75NTR = p75 neurotrophin receptor
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Glicoproteínas
/
Expresión Génica
/
Proteínas de la Matriz Extracelular
/
Metaloproteinasa 3 de la Matriz
/
Factor de Crecimiento Nervioso
/
Lipocalinas
/
Degeneración del Disco Intervertebral
Tipo de estudio:
Prognostic_studies
Límite:
Animals
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Humans
/
Male
Idioma:
En
Revista:
J Neurosurg Spine
Asunto de la revista:
NEUROCIRURGIA
Año:
2014
Tipo del documento:
Article
Pais de publicación:
Estados Unidos