The presence of the pAA plasmid in the German O104:H4 Shiga toxin type 2a (Stx2a)-producing enteroaggregative Escherichia coli strain promotes the translocation of Stx2a across an epithelial cell monolayer.

Boisen, Nadia; Hansen, Anne-Marie; Melton-Celsa, Angela R; Zangari, Tonia; Mortensen, Ninell Pollas; Kaper, James B; O'Brien, Alison D; Nataro, James P

Boisen, Nadia; Hansen, Anne-Marie; Melton-Celsa, Angela R; Zangari, Tonia; Mortensen, Ninell Pollas; Kaper, James B; O'Brien, Alison D; Nataro, James P.

Afiliación

Boisen N; Department of Pediatrics, University of Virginia School of Medicine, Charlottesville.
Hansen AM; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore.
Melton-Celsa AR; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Zangari T; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Mortensen NP; Technology for Industry and the Environment, Discovery-Science-Technology, RTI International, Research Triangle Park, North Carolina Biological and Nanoscale Systems, BioSciences Division, Oak Ridge National Laboratory, Tennessee.
Kaper JB; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore.
O'Brien AD; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Nataro JP; Department of Pediatrics, University of Virginia School of Medicine, Charlottesville.

J Infect Dis ; 210(12): 1909-19, 2014 Dec 15.

Article en En | MEDLINE | ID: mdl-25038258

Asunto(s)

Células Epiteliales/metabolismo; Escherichia coli/metabolismo; Transporte de Proteínas; Toxina Shiga II/metabolismo; Adhesión Bacteriana; Línea Celular; Escherichia coli/clasificación; Escherichia coli/genética; Escherichia coli/aislamiento & purificación; Infecciones por Escherichia coli/microbiología; Proteínas de Escherichia coli/genética; Proteínas de Escherichia coli/metabolismo; Eliminación de Gen; Genotipo; Alemania; Humanos; Interleucina-8/metabolismo; Plásmidos; Serogrupo; Transactivadores/genética; Transactivadores/metabolismo; Factores de Virulencia/genética; Factores de Virulencia/metabolismo

Palabras clave

O104:H4; Shiga toxin; diarrhea; enteroaggregative Escherichia coli (EAEC); pAA plasmid

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Toxina Shiga II / Transporte de Proteínas / Células Epiteliales / Escherichia coli Límite: Humans País/Región como asunto: Europa Idioma: En Revista: J Infect Dis Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos

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