HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activation.

Nural-Guvener, Hikmet F; Zakharova, Luidmila; Nimlos, James; Popovic, Snjezana; Mastroeni, Diego; Gaballa, Mohamed A

Nural-Guvener, Hikmet F; Zakharova, Luidmila; Nimlos, James; Popovic, Snjezana; Mastroeni, Diego; Gaballa, Mohamed A.

Afiliación

Nural-Guvener HF; Cardiovascular Research Laboratory, Banner Sun Health Research Institute, 10515 W. Santa Fe Drive, Sun City, AZ 85351, USA.
Zakharova L; Cardiovascular Research Laboratory, Banner Sun Health Research Institute, 10515 W. Santa Fe Drive, Sun City, AZ 85351, USA.
Nimlos J; Cardiovascular Research Laboratory, Banner Sun Health Research Institute, 10515 W. Santa Fe Drive, Sun City, AZ 85351, USA.
Popovic S; Cardiovascular Research Laboratory, Banner Sun Health Research Institute, 10515 W. Santa Fe Drive, Sun City, AZ 85351, USA.
Mastroeni D; L. J Roberts Center for Alzheimer's Research at Banner Sun Health Research Institute, Sun City, AZ, USA.
Gaballa MA; Cardiovascular Research Laboratory, Banner Sun Health Research Institute, 10515 W. Santa Fe Drive, Sun City, AZ 85351, USA.

Fibrogenesis Tissue Repair ; 7: 10, 2014.

Article en En | MEDLINE | ID: mdl-25024745

Palabras clave

Congestive heart failure; Fibrosis; HDAC; Mocetinostat; Myocardial Infarction; Myofibroblast; Rat

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Fibrogenesis Tissue Repair Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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