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Evaluation of a predictive model for pancreatic fistula based on amylase value in drains after pancreatic resection.
Partelli, Stefano; Tamburrino, Domenico; Crippa, Stefano; Facci, Enrico; Zardini, Claudio; Falconi, Massimo.
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  • Partelli S; Department of Surgery, Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy.
  • Tamburrino D; Department of Surgery, Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy.
  • Crippa S; Department of Surgery, Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy.
  • Facci E; Department of Surgery, Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy.
  • Zardini C; Department of Surgery, Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy.
  • Falconi M; Department of Surgery, Ospedale Sacro Cuore Don Calabria, Negrar, Verona, Italy. Electronic address: m.falconi@univpm.it.
Am J Surg ; 208(4): 634-9, 2014 Oct.
Article en En | MEDLINE | ID: mdl-25001423
BACKGROUND: Amylase value in drains (AVD) is a predictor of pancreatic fistula (PF). We evaluated the accuracy of an AVD-based model. METHODS: Two hundred thirty-one patients underwent pancreatoduodenectomy with pancreaticojejunostomy (PDPJ) or pancreatoduodenectomy with duct-to-mucosa (PDDTM) and distal pancreatectomy (DP). Patients with AVD greater than 5,000 U/L on postoperative day (POD) 1 underwent AVD measurement on POD5. RESULTS: Sensitivity and specificity of POD1 AVD greater than 5,000 in predicting PF were 71% and 90%, respectively. The sensitivity and specificity of POD5 AVD greater than 200 were 90% and 83%, respectively. AVD greater than 1,000 (for PDPJ) and 2,000 U/L (PDDTM and DP) represented the most accurate cutoffs on POD1. AVD greater than 200 (PDPJ), 300 (PDDTM), and 50 U/L (DP) represented the cutoffs with the highest sensitivity in predicting PF on POD5. CONCLUSION: AVD-based model for predicting PF after pancreatic resection is an accurate tool, although AVD cutoffs should be evaluated for each type of operation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancreatectomía / Neoplasias Pancreáticas / Complicaciones Posoperatorias / Drenaje / Fístula Pancreática / Amilasas Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Surg Año: 2014 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancreatectomía / Neoplasias Pancreáticas / Complicaciones Posoperatorias / Drenaje / Fístula Pancreática / Amilasas Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Surg Año: 2014 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos