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Respiratory modulation of cardiac vagal tone in Lyme disease.
Puri, Basant K; Shah, Mussadiq; Monro, Jean A; Kingston, Michele C; Julu, Peter Oo.
Afiliación
  • Puri BK; Basant K Puri, Department of Medicine, Imperial College London, Hammersmith Hospital, London W12 0HS, United Kingdom.
  • Shah M; Basant K Puri, Department of Medicine, Imperial College London, Hammersmith Hospital, London W12 0HS, United Kingdom.
  • Monro JA; Basant K Puri, Department of Medicine, Imperial College London, Hammersmith Hospital, London W12 0HS, United Kingdom.
  • Kingston MC; Basant K Puri, Department of Medicine, Imperial College London, Hammersmith Hospital, London W12 0HS, United Kingdom.
  • Julu PO; Basant K Puri, Department of Medicine, Imperial College London, Hammersmith Hospital, London W12 0HS, United Kingdom.
World J Cardiol ; 6(6): 502-6, 2014 Jun 26.
Article en En | MEDLINE | ID: mdl-24976922
AIM: To conduct the first systematic test of the hypothesis that modulation of cardiac vagal tone is impaired in Lyme disease. METHODS: The response of cardiac vagal tone to respiratory modulation was measured in 18 serologically positive Lyme disease patients and in 18 controls. RESULTS: The two groups were matched in respect of age, sex, body mass, mean arterial blood pressure, mean resting heart rate and mean resting cardiac vagal tone. The mean maximum cardiac vagal tone during deep breathing in the Lyme disease patients [11.2 (standard error 1.3)] was lower than in the matched controls [16.5 (standard error 1.7); P = 0.02]. CONCLUSION: Respiratory modulation of cardiac vagal tone is impaired in Lyme disease, which suggests that Lyme disease may directly affect the vagus nerve or the brainstem.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: World J Cardiol Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: World J Cardiol Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos