Your browser doesn't support javascript.
loading
Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy.
Idiz, Oguz; Aysan, Erhan; Firat, Deniz; Ersoy, Yeliz Emine; Cengiz, Merve Busra; Akbulut, Huseyin; Isik, Arda; Muslumanoglu, Mahmut.
Afiliación
  • Idiz O; Department of General Surgery, Bezmialem University, Istanbul, Turkey.
  • Aysan E; Department of General Surgery, Bezmialem University, Istanbul, Turkey.
  • Firat D; Department of General Surgery, Erzincan University, Erzincan, Turkey.
  • Ersoy YE; Department of General Surgery, Bezmialem University, Istanbul, Turkey.
  • Cengiz MB; Department of General Surgery, Bezmialem University, Istanbul, Turkey.
  • Akbulut H; Department of General Surgery, Bezmialem University, Istanbul, Turkey.
  • Isik A; Department of General Surgery, Erzincan University, Erzincan, Turkey.
  • Muslumanoglu M; Department of General Surgery, Bezmialem University, Istanbul, Turkey.
Med Sci Monit ; 20: 1090-4, 2014 Jun 28.
Article en En | MEDLINE | ID: mdl-24973306
BACKGROUND: We evaluated the effects of local flax seed oil and glycerol application for reducing adhesion formation after thyroidectomy. MATERIAL AND METHODS: We randomly assigned 18 female Wistar albino rats (median weight: 275 g, median age: 4.5 mth) to 3 groups: 0.1 ml 0.9% NaCl, glycerol, and flax seed oil were sprayed in a perithyroidal area after thyroidectomy operation on all animals as anti-adhesive barriers. Rats were sacrificed on the postoperative 14th day and adhesions were evaluated macroscopically and microscopically. RESULTS: The median macroscopic adhesion score was 3.0±0.0 in the 0.9% NaCl group, 1.33±0.52 in the glycerol group, and 1.67±0.53 in the flax seed oil group. The median histopathological fibrosis scores were 2.33±0.82, 0.67±0.52, and 0.83±0.75, respectively. Both glycerol and flaxseed oil group macroscopic and microscopic scores were significantly lower than the 0.9% NaCl group (p<0.05). There was no significant difference among the groups (p>0.05). CONCLUSIONS: Glycerol and flax seed oil both decrease the incidence of post-thyroidectomy adhesion in rats, but glycerol is more effective.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiroidectomía / Aceite de Linaza / Adherencias Tisulares / Glicerol Límite: Animals Idioma: En Revista: Med Sci Monit Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiroidectomía / Aceite de Linaza / Adherencias Tisulares / Glicerol Límite: Animals Idioma: En Revista: Med Sci Monit Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos