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Non-equivalent ligand selectivity of agonist sites in (α4ß2)2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy.
Mazzaferro, Simone; Gasparri, Federica; New, Karina; Alcaino, Constanza; Faundez, Manuel; Iturriaga Vasquez, Patricio; Vijayan, Ranjit; Biggin, Philip C; Bermudez, Isabel.
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  • Mazzaferro S; From the Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom.
  • Gasparri F; From the Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom.
  • New K; From the Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom.
  • Alcaino C; From the Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom.
  • Faundez M; the Department of Chemistry, Faculty of Sciences, University of Chile, Santiago, Chile.
  • Iturriaga Vasquez P; the Department of Chemistry, Faculty of Sciences, University of Chile, Santiago, Chile.
  • Vijayan R; Department of Biology, College of Science, United Arab Emirates University, Al Ain, United Arab Emirates, and.
  • Biggin PC; Structural Bioinformatics and Computational Biochemistry, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom.
  • Bermudez I; From the Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom, ibermudez@brookes.ac.uk.
J Biol Chem ; 289(31): 21795-806, 2014 Aug 01.
Article en En | MEDLINE | ID: mdl-24936069
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Nicotínicos / Agonistas Nicotínicos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Nicotínicos / Agonistas Nicotínicos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos