[Whole genome analysis of human group A rotavirus G9p[8] strains in Hebei lulong region, 2009-2011].
Bing Du Xue Bao
; 30(2): 119-27, 2014 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-24923163
Abstract:This study aims to investigate the genetic characteristics of group A rotavirus (GARV) G9P[8] strains from infantile diarrhea samples in Hebei Lulong region from 2009 to 2011. We randomly selected five GARV G9P[8] strains in Hebei Lulong region from 2009 to 2011, amplified the 11 gene fragments of GARVs by RT-PCR, and analyz their full-genome sequences by homology and phylogenetic analysis with DNAStar and MEGA. The nucleotide homology between strains LL11131077 and LL11131083 in 2011 was significantly higher than hat etween them and the other three strains in 2009 and 2010. The G9P[8] GARVs circulating in Hebei Lulong region from 2009 to 2011 elenged to the same genotype as the prevalent G9P[8] GARVs in other parts of the world. However,the two strains in 2011, compared with those in 2009 and 2010, were located in a different sub-branch of the phylogenetic tree and had amino acid mutations at many sites.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Rotavirus
/
Genoma Viral
/
Rotavirus
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Bing Du Xue Bao
Asunto de la revista:
VIROLOGIA
Año:
2014
Tipo del documento:
Article
Pais de publicación:
China