[Case report of a patient with advanced and disseminated gastric carcinoma treated by s-1]. / Kazuistika pacienta se znacne pokrocilým a diseminovaným karcinomem zaludku léceným preparátem S-1.
Klin Onkol
; 27(3): 207-9, 2014.
Article
en Cs
| MEDLINE
| ID: mdl-24918280
BACKGROUND: Prognosis of patients with metastatic gastric cancer is abysmal, usually just a few months. S-1 is a peroral fluoropyrimidine antitumor drug. It is a fixed combination of three effective drugs - tegafur, gimeracil and oteracil potassium. CASE: This is a case report of a 71-year-old man treated for local advanced and metastatic gastric carcinoma treated with combination of S-1 and cisplatin as a first line of therapy. Treatment response reached partial remission and lasted for six months. Treatment was very well tolerated, with no grade 3 and 4 toxicity. After progression, the patient was treated with further lines of therapy. CONCLUSION: In the Czech Republic, experience with S-1 drug is very limited. Our case report showed a good treatment response and minimal toxicity of this treatment, in concordance with results of the study FLAGS.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácido Oxónico
/
Neoplasias Gástricas
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Tegafur
Tipo de estudio:
Prognostic_studies
Límite:
Aged
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
Cs
Revista:
Klin Onkol
Asunto de la revista:
NEOPLASIAS
Año:
2014
Tipo del documento:
Article
Pais de publicación:
República Checa