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Synthesis, biological evaluation and molecular modeling of 1,3,4-thiadiazol-2-amide derivatives as novel antitubulin agents.
Li, Yu-Jing; Qin, Ya-Juan; Makawana, Jigar A; Wang, Yan-Ting; Zhang, Yan-Qing; Zhang, Ya-Liang; Yang, Meng-Ru; Jiang, Ai-Qin; Zhu, Hai-Liang.
Afiliación
  • Li YJ; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: liyujing19890210@126.com.
  • Qin YJ; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: qingyajuanhebei@163.com.
  • Makawana JA; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: Jigar.makawana@gmail.com.
  • Wang YT; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: wangyanting2012@qq.com.
  • Zhang YQ; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: zyq198903@126.com.
  • Zhang YL; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: zhyl.hope.2008@163.com.
  • Yang MR; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: yangmengru34@126.com.
  • Jiang AQ; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: jianaq@nju.edu.cn.
  • Zhu HL; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, PR China; School of Medicine, Nanjing University, Nanjing 210093, PR China. Electronic address: zhuhl@nju.edu.cn.
Bioorg Med Chem ; 22(15): 4312-22, 2014 Aug 01.
Article en En | MEDLINE | ID: mdl-24909678
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Moduladores de Tubulina / Amidas / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Moduladores de Tubulina / Amidas / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido