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Identification of potent and selective glucosylceramide synthase inhibitors from a library of N-alkylated iminosugars.
Ghisaidoobe, Amar; Bikker, Pieter; de Bruijn, Arjan C J; Godschalk, Frithjof D; Rogaar, Eva; Guijt, Marieke C; Hagens, Peter; Halma, Jerre M; Van't Hart, Steven M; Luitjens, Stijn B; van Rixel, Vincent H S; Wijzenbroek, Mark; Zweegers, Thor; Donker-Koopman, Wilma E; Strijland, Anneke; Boot, Rolf; van der Marel, Gijs; Overkleeft, Herman S; Aerts, Johannes M F G; van den Berg, Richard J B H N.
Afiliación
  • Ghisaidoobe A; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Bikker P; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • de Bruijn AC; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Godschalk FD; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Rogaar E; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Guijt MC; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Hagens P; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Halma JM; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Van't Hart SM; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Luitjens SB; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • van Rixel VH; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Wijzenbroek M; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Zweegers T; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Donker-Koopman WE; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
  • Strijland A; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
  • Boot R; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
  • van der Marel G; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Overkleeft HS; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
  • Aerts JM; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
  • van den Berg RJ; Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
ACS Med Chem Lett ; 2(2): 119-23, 2011 Feb 10.
Article en En | MEDLINE | ID: mdl-24900289
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: ACS Med Chem Lett Año: 2011 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: ACS Med Chem Lett Año: 2011 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos