Strategies for measuring the rate of age-related cataract formation in vivo.
Lens Eye Toxic Res
; 6(4): 515-22, 1989.
Article
en En
| MEDLINE
| ID: mdl-2487269
The Lens Opacities Classification System (LOCS II) has been tested as a method for detecting and grading longitudinal changes in cataract severity. The LOCS I and II systems have already been tested and validated for cross-sectional classification of human cataracts in vivo. 130 eyes (of 68 patients) were photographed at baseline and follow-up visits with Neitz CTR and Zeiss slit photography. The mean length of follow-up was 14.7 +/- 4.4 months. The severity of nuclear opalescence (NO), cortical (C) and posterior subcapular cataract (P) was graded in a masked fashion using the LOCS II standards. Side-by-side comparisons of baseline and follow-up photos were also done in a masked fashion to detect more subtle changes than might be evident in the LOCS II gradings. The annual percent progression in cataracts graded by LOCS II standards are: (NO): 12.4%, (C): 17.9%, and (P): 6.5%. The LOCS II standards are offered as a promising subjective method for longitudinal grading of human cataractous change in vivo.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Catarata
/
Envejecimiento
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Lens Eye Toxic Res
Asunto de la revista:
OFTALMOLOGIA
Año:
1989
Tipo del documento:
Article
Pais de publicación:
Estados Unidos