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The effectiveness of gadolinium MRI to improve target delineation for radiotherapy in hepatocellular carcinoma: a comparative study of rigid image registration techniques.
Yang, D S; Yoon, W S; Lee, J A; Lee, N K; Lee, S; Kim, C Y; Yim, H J; Lee, S H; Chung, H H; Cha, S H.
Afiliación
  • Yang DS; Department of Radiation Oncology, Guro Hospital, College of Medicine, Korea University, Seoul, Republic of Korea.
  • Yoon WS; Department of Radiation Oncology, Ansan Hospital, College of Medicine, Korea University, Ansan, Republic of Korea. Electronic address: irionyws@korea.ac.kr.
  • Lee JA; Department of Radiation Oncology, Guro Hospital, College of Medicine, Korea University, Seoul, Republic of Korea.
  • Lee NK; Department of Radiation Oncology, Anam Hospital, College of Medicine, Korea University, Seoul, Republic of Korea.
  • Lee S; Department of Radiation Oncology, Anam Hospital, College of Medicine, Korea University, Seoul, Republic of Korea.
  • Kim CY; Department of Radiation Oncology, Anam Hospital, College of Medicine, Korea University, Seoul, Republic of Korea.
  • Yim HJ; Department of Internal Medicine, Ansan Hospital, College of Medicine, Korea University, Ansan, Republic of Korea.
  • Lee SH; Department of Radiology, Ansan Hospital, College of Medicine, Korea University, Ansan, Republic of Korea.
  • Chung HH; Department of Radiology, Ansan Hospital, College of Medicine, Korea University, Ansan, Republic of Korea.
  • Cha SH; Department of Radiology, Ansan Hospital, College of Medicine, Korea University, Ansan, Republic of Korea.
Phys Med ; 30(6): 676-81, 2014 Sep.
Article en En | MEDLINE | ID: mdl-24870246
To achieve consistent target delineation in radiotherapy for hepatocellular carcinoma (HCC), image registration between simulation CT and diagnostic MRI was explored. Twenty patients with advanced HCC were included. The median interval between MRI and CT was 11 days. CT was obtained with shallow free breathing and MRI at exhale phase. On each CT and MRI, the liver and the gross target volume (GTV) were drawn. A rigid image registration was taken according to point information of vascular bifurcation (Method[A]) and pixel information of volume of interest only including the periphery of the liver (Method[B]) and manually drawn liver (Method[C]). In nine cases with an indefinite GTV on CT, a virtual sphere was generated at the epicenter of the GTV. The GTV from CT (VGTV[CT]) and MRI (VGTV[MR]) and the expanded GTV from MRI (V+GTV[MR]) considering geometrical registration error were defined. The underestimation (uncovered V[CT] by V[MR]) and the overestimation (excessive V[MR] by V[CT]) were calculated. Through a paired T-test, the difference between image registration techniques was analyzed. For method[A], the underestimation rates of VGTV[MR] and V+GTV[MR] were 16.4 ± 8.9% and 3.2 ± 3.7%, and the overestimation rates were 16.6 ± 8.7% and 28.4 ± 10.3%, respectively. For VGTV[MR] and V+GTV[MR], the underestimation rates and overestimation rates of method[A] were better than method[C]. The underestimation rates and overestimation rates of the VGTV[MR] were better in method[B] than method[C]. By image registration and additional margin, about 97% of HCC could be covered. Method[A] or method[B] could be recommended according to physician preference.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento de Imagen Asistido por Computador / Carcinoma Hepatocelular / Radioterapia Guiada por Imagen / Gadolinio / Neoplasias Hepáticas Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Phys Med Asunto de la revista: BIOFISICA / BIOLOGIA / MEDICINA Año: 2014 Tipo del documento: Article Pais de publicación: Italia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento de Imagen Asistido por Computador / Carcinoma Hepatocelular / Radioterapia Guiada por Imagen / Gadolinio / Neoplasias Hepáticas Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Phys Med Asunto de la revista: BIOFISICA / BIOLOGIA / MEDICINA Año: 2014 Tipo del documento: Article Pais de publicación: Italia