Inactivation of the adrenergic receptor ß2 disrupts glucose homeostasis in mice.

Fernandes, Gustavo W; Ueta, Cintia B; Fonseca, Tatiane L; Gouveia, Cecilia H A; Lancellotti, Carmen L; Brum, Patrícia C; Christoffolete, Marcelo A; Bianco, Antonio C; Ribeiro, Miriam O

Fernandes, Gustavo W; Ueta, Cintia B; Fonseca, Tatiane L; Gouveia, Cecilia H A; Lancellotti, Carmen L; Brum, Patrícia C; Christoffolete, Marcelo A; Bianco, Antonio C; Ribeiro, Miriam O.

Afiliación

Fernandes GW; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Ueta CB; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Fonseca TL; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Gouveia CH; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Lancellotti CL; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Brum PC; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Christoffolete MA; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Bianco AC; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,
Ribeiro MO; Presbyterian University Mackenzie - Biological ScienceCCBS, São Paulo, SP, BrazilInstitute of Science Biomedical - Morpho-Functional SciencesAv. Prof. Lineu Prestes, São Paulo, SP 04310-000, BrazilDepartment of Cell and Developmental BiologyInstitute of Biomedical Sciences, University of Sao Paulo,

J Endocrinol ; 221(3): 381-90, 2014 Jun.

Article en En | MEDLINE | ID: mdl-24868110

Asunto(s)

Tejido Adiposo Pardo/metabolismo; Glucosa/metabolismo; Homeostasis/fisiología; Receptores Adrenérgicos beta 2/deficiencia; Termogénesis/fisiología; Tejido Adiposo Pardo/efectos de los fármacos; Animales; Western Blotting; Dieta Alta en Grasa/efectos adversos; Dobutamina/farmacología; Ayuno/sangre; Hígado Graso/etiología; Hígado Graso/genética; Hígado Graso/metabolismo; Expresión Génica; Homeostasis/genética; Hiperinsulinismo/sangre; Canales Iónicos/genética; Canales Iónicos/metabolismo; Masculino; Ratones; Ratones Noqueados; Proteínas Mitocondriales/genética; Proteínas Mitocondriales/metabolismo; Norepinefrina/farmacología; Obesidad/etiología; Obesidad/genética; Obesidad/metabolismo; Fosfoenolpiruvato Carboxiquinasa (GTP)/genética; Fosfoenolpiruvato Carboxiquinasa (GTP)/metabolismo; Receptores Adrenérgicos beta 2/genética; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Termogénesis/genética; Proteína Desacopladora 1

Palabras clave

adaptive thermogenesis; brown adipose tissue (BAT); obesity; ß-adrenergic receptors

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tejido Adiposo Pardo / Receptores Adrenérgicos beta 2 / Termogénesis / Glucosa / Homeostasis Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: J Endocrinol Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido

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