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Association between Smoking and Health Outcomes in Postmenopausal Women Living with Multiple Sclerosis.
Jawahar, Rachel; Oh, Unsong; Eaton, Charles; Wright, Nicole; Tindle, Hilary; Lapane, Kate L.
Afiliación
  • Jawahar R; Department of Epidemiology and Community Health, Virginia Commonwealth University School, Richmond, VA 23284, USA.
  • Oh U; Department of Neurology, Virginia Commonwealth University School, Richmond, VA 23284, USA.
  • Eaton C; Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Pawtucket, RI 02861, USA.
  • Wright N; Department of Epidemiology, University of Alabama Birmingham, Birmingham, AL 35294, USA.
  • Tindle H; Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.
  • Lapane KL; Department of Quantitative Health Sciences, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Mult Scler Int ; 2014: 686045, 2014.
Article en En | MEDLINE | ID: mdl-24860668
Background. In multiple sclerosis (MS), symptom management and improved health-related quality of life (HrQOL) may be modified by smoking. Objective. To evaluate the extent to which smoking is associated with worsened health outcomes and HrQOL for postmenopausal women with MS. Methods. We identified 251 Women's Health Initiative Observational Study participants with a self-reported MS diagnosis. Using a linear model, we estimated changes from baseline to 3 years for activities of daily living, total metabolic equivalent tasks (MET) hours per week, mental and physical component scales (MCS, PCS) of the SF-36, and menopausal symptoms adjusting for years since menopause and other confounders. Results. Nine percent were current and 50% past smokers. Age at smoking initiation was associated with significant changes in MCS during menopause. PCS scores were unchanged. While women who had ever smoked experienced an increase in physical activity during menopause, the physical activity levels of women who never smoked declined. Residual confounding may explain this finding. Smoking was not associated with change in menopausal symptoms during the 3-year follow-up. Conclusion. Smoking was not associated with health outcomes among post-menopausal women with MS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Idioma: En Revista: Mult Scler Int Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Egipto
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Idioma: En Revista: Mult Scler Int Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Egipto