Your browser doesn't support javascript.
loading
HbA1c can be a useful glycemic control marker for patients with neonatal diabetes mellitus older than 20 weeks of age.
Furuya, Akiko; Suzuki, Shigeru; Koga, Masafumi; Oshima, Miho; Amamiya, Satoshi; Nakao, Atsushi; Wada, Keiko; Okuhara, Koji; Hayano, Satoshi; Matsuo, Kumihiro; Tanahashi, Yusuke; Azuma, Hiroshi.
Afiliación
  • Furuya A; Department of Pediatrics, Asahikawa Medical University, 2-1-1-1, Midorigaoka Higashi, Asahikawa 078-8510, Japan.
  • Suzuki S; Department of Pediatrics, Asahikawa Medical University, 2-1-1-1, Midorigaoka Higashi, Asahikawa 078-8510, Japan. Electronic address: shige5p@asahikawa-med.ac.jp.
  • Koga M; Department of Internal Medicine, Kawanishi City Hospital, Japan.
  • Oshima M; Department of Pediatrics, Sapporo Tokushukai Hospital, Japan.
  • Amamiya S; Department of Pediatrics, Sapporo Tokushukai Hospital, Japan.
  • Nakao A; Department of Neonatology, Japanese Red Cross Medical Center, Japan.
  • Wada K; Department of Pediatrics, Bell Land General Hospital, Japan; Department of Neonatology, Hyogo Prefectural Kobe Children's Hospital, Japan.
  • Okuhara K; Department of Pediatrics, Tenshi Hospital, Japan.
  • Hayano S; Department of Pediatrics, Anjo Kosei Hospital, Japan.
  • Matsuo K; Department of Pediatrics, Asahikawa Medical University, 2-1-1-1, Midorigaoka Higashi, Asahikawa 078-8510, Japan.
  • Tanahashi Y; Department of Pediatrics, Asahikawa Medical University, 2-1-1-1, Midorigaoka Higashi, Asahikawa 078-8510, Japan.
  • Azuma H; Department of Pediatrics, Asahikawa Medical University, 2-1-1-1, Midorigaoka Higashi, Asahikawa 078-8510, Japan.
Clin Chim Acta ; 436: 93-6, 2014 Sep 25.
Article en En | MEDLINE | ID: mdl-24854496
BACKGROUND: The accuracy of most HbA1c analysis methods is affected by the presence of increased fetal hemoglobin (HbF). The objective of this study was to investigate the age at which HbA1c measurements become useful for monitoring glycemic control in patients with neonatal diabetes mellitus (NDM). METHODS: We retrospectively analyzed the data of 5 NDM patients diagnosed at 38±20 days of age, who each had several available HbA1c measurements during the first year of life, with a control group of HbA1c values over the course of 1 year for 13 patients with type 1 diabetes mellitus (T1DM). Mean blood glucose (MBG) levels derived from premeal or premeal plus bedtime blood glucose measurements prior to HbA1c measurements were compared to HbA1c values. RESULTS: The NDM patients' age at which the difference in the HbA1c/MBG ratios became not significant between the NDM patients and the T1DM patients was 21 weeks of age and over. Even after the HbA1c was adjusted for HbF, this ratio was significantly lower in the NDM patients at <21 weeks of age than in the T1DM patients. CONCLUSIONS: HbA1c can be a useful glycemic control marker for NDM patients >20 weeks of age.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucemia / Hemoglobina Glucada / Diabetes Mellitus Tipo 1 Tipo de estudio: Observational_studies Límite: Adolescent / Female / Humans / Infant / Male / Newborn Idioma: En Revista: Clin Chim Acta Año: 2014 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucemia / Hemoglobina Glucada / Diabetes Mellitus Tipo 1 Tipo de estudio: Observational_studies Límite: Adolescent / Female / Humans / Infant / Male / Newborn Idioma: En Revista: Clin Chim Acta Año: 2014 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos