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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Mazur, Pawel K; Reynoird, Nicolas; Khatri, Purvesh; Jansen, Pascal W T C; Wilkinson, Alex W; Liu, Shichong; Barbash, Olena; Van Aller, Glenn S; Huddleston, Michael; Dhanak, Dashyant; Tummino, Peter J; Kruger, Ryan G; Garcia, Benjamin A; Butte, Atul J; Vermeulen, Michiel; Sage, Julien; Gozani, Or.
Afiliación
  • Mazur PK; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA [3].
  • Reynoird N; 1] Department of Biology, Stanford University, California 94305, USA [2].
  • Khatri P; Institute for Immunity, Transplantation and Infection, and Department of Medicine, Stanford University School of Medicine, California 94305, USA.
  • Jansen PW; Department of Molecular Cancer Research and Department of Medical Oncology, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.
  • Wilkinson AW; Department of Biology, Stanford University, California 94305, USA.
  • Liu S; Epigenetics Program and Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Barbash O; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.
  • Van Aller GS; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.
  • Huddleston M; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.
  • Dhanak D; 1] Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA [2] Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, USA (D.D.); Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences
  • Tummino PJ; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.
  • Kruger RG; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.
  • Garcia BA; Epigenetics Program and Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Butte AJ; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA.
  • Vermeulen M; 1] Department of Molecular Cancer Research and Department of Medical Oncology, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands [2] Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, USA (D.D.); Department of Molecular Biology, Faculty of Science
  • Sage J; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA [3].
  • Gozani O; 1] Department of Biology, Stanford University, California 94305, USA [2].
Nature ; 510(7504): 283-7, 2014 Jun 12.
Article en En | MEDLINE | ID: mdl-24847881
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína Oncogénica p21(ras) / Transformación Celular Neoplásica / N-Metiltransferasa de Histona-Lisina / Quinasas Quinasa Quinasa PAM / MAP Quinasa Quinasa Quinasa 2 / Lisina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína Oncogénica p21(ras) / Transformación Celular Neoplásica / N-Metiltransferasa de Histona-Lisina / Quinasas Quinasa Quinasa PAM / MAP Quinasa Quinasa Quinasa 2 / Lisina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido