Your browser doesn't support javascript.
loading
Investigation of the Efficacy of the Cone Location and Magnitude Index in the Diagnosis of Keratoconus.
Kocamis, Sücattin Ilker; Çakmak, Hasan Basri; Çagil, Nurullah; Toklu, Yasin.
Afiliación
  • Kocamis SI; a Ophthalmology Department , Ardahan State Hospital , Ardahan , Turkey .
  • Çakmak HB; b Ophthalmology Department , Yildirim Beyazit University School of Medicine , Ankara , Turkey , and.
  • Çagil N; b Ophthalmology Department , Yildirim Beyazit University School of Medicine , Ankara , Turkey , and.
  • Toklu Y; c Ankara Atatürk Training and Research Hospital Ophthalmology Department , Ankara , Turkey.
Semin Ophthalmol ; 31(3): 203-9, 2016.
Article en En | MEDLINE | ID: mdl-24840348
PURPOSE: The aim of this study was to investigate the sensitivity, specificity, and accuracy of The Cone Location and Magnitude Index (CLMI) in keratoconus diagnosis. METHODS: 301 eyes of 159 keratoconus patients and 394 eyes of 265 refractive surgery candidates as a control group were enrolled in this retrospective clinical study. CLMI was compared with keratometric corneal topography parameters, wavefront aberrations, and pachymetry data derived from optical coherence tomography using independent sample t-tests and ROC curves. Logistic regression analysis was applied to determine the most accurate parameter in keratoconus diagnosis. Pearson's correlation analysis was used to determine the correlation between CLMI and the other measurements. RESULTS: Average axial CLMI (aCLMI) was 8.19 ± 6.15 D in the keratoconus group and 0.83 ± 0.62 D in the control group (p = 0.001). aCLMI had the greatest sensitivity (89%), specificity (94%), and accuracy (92%) for the keratoconus diagnosis at the best cut-off point of 1.82 according to the ROC curve. Logistic regression analysis selected aCLMI as the most accurate measurement among the other parameters (accuracy 92.8%). aCLMI showed strongest correlations with coma-like aberrations (r = 0.881), total high-order aberrations (r = 0.858), and vertical coma (r = -0.814), respectively. CONCLUSION: CLMI is a robust index for screening keratoconus with high sensitivity, specificity, and accuracy.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Córnea / Queratocono Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Semin Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Córnea / Queratocono Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Semin Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido