Development and validation of a computational model of the knee joint for the evaluation of surgical treatments for osteoarthritis.
Comput Methods Biomech Biomed Engin
; 17(13): 1502-17, 2014.
Article
en En
| MEDLINE
| ID: mdl-24786914
A three-dimensional (3D) knee joint computational model was developed and validated to predict knee joint contact forces and pressures for different degrees of malalignment. A 3D computational knee model was created from high-resolution radiological images to emulate passive sagittal rotation (full-extension to 65°-flexion) and weight acceptance. A cadaveric knee mounted on a six-degree-of-freedom robot was subjected to matching boundary and loading conditions. A ligament-tuning process minimised kinematic differences between the robotically loaded cadaver specimen and the finite element (FE) model. The model was validated by measured intra-articular force and pressure measurements. Percent full scale error between FE-predicted and in vitro-measured values in the medial and lateral compartments were 6.67% and 5.94%, respectively, for normalised peak pressure values, and 7.56% and 4.48%, respectively, for normalised force values. The knee model can accurately predict normalised intra-articular pressure and forces for different loading conditions and could be further developed for subject-specific surgical planning.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Osteoartritis
/
Simulación por Computador
/
Articulación de la Rodilla
/
Modelos Anatómicos
Tipo de estudio:
Prognostic_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Comput Methods Biomech Biomed Engin
Asunto de la revista:
ENGENHARIA BIOMEDICA
/
FISIOLOGIA
Año:
2014
Tipo del documento:
Article
Pais de publicación:
Reino Unido