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Contamination risk for operators performing semi-closed HIPEC procedure using cisplatin.
Caneparo, A; Massucco, P; Vaira, M; Maina, G; Giovale, E; Coggiola, M; Cinquegrana, A; Robella, M; De Simone, M.
Afiliación
  • Caneparo A; Division of Surgical Oncology, Candiolo Cancer Institute - FPO, IRCCS, Strada Provinciale 142, Km. 3.95, 10060 Candiolo, Torino, Italy. Electronic address: documenti.caneparo@gmail.com.
  • Massucco P; Division of Surgical Oncology, Candiolo Cancer Institute - FPO, IRCCS, Strada Provinciale 142, Km. 3.95, 10060 Candiolo, Torino, Italy.
  • Vaira M; Division of Surgical Oncology, Candiolo Cancer Institute - FPO, IRCCS, Strada Provinciale 142, Km. 3.95, 10060 Candiolo, Torino, Italy.
  • Maina G; Department of Clinical and Biological Sciences, University of Turin, Orthopedics and Trauma Center (CTO), Via Gianfranco Zuretti, 29, 10126 Turin, Italy.
  • Giovale E; Prevention and Protection Service, Candiolo Cancer Institute - FPO, IRCCS, Strada Provinciale 142, Km. 3.95, 10060 Candiolo, Torino, Italy.
  • Coggiola M; Division of Occupational Medicine, City of Health and Science Hospital, Orthopedics and Trauma Center (CTO), Via Gianfranco Zuretti, 29, 10126 Turin, Italy.
  • Cinquegrana A; Division of Surgical Oncology, Candiolo Cancer Institute - FPO, IRCCS, Strada Provinciale 142, Km. 3.95, 10060 Candiolo, Torino, Italy.
  • Robella M; Division of Surgical Oncology, Candiolo Cancer Institute - FPO, IRCCS, Strada Provinciale 142, Km. 3.95, 10060 Candiolo, Torino, Italy.
  • De Simone M; Division of Surgical Oncology, Candiolo Cancer Institute - FPO, IRCCS, Strada Provinciale 142, Km. 3.95, 10060 Candiolo, Torino, Italy.
Eur J Surg Oncol ; 40(8): 925-9, 2014 Aug.
Article en En | MEDLINE | ID: mdl-24726786
AIMS: Aim of this study was to assess operators' safety while performing a semi-closed HIPEC procedure for peritoneal carcinomatosis using cisplatin drugs. METHODS: Environmental air, theater personnel urine, operators' gloves and hand skin contamination were assessed during two non-consecutive working days. Six operating surgeons, two anesthesiologists and two theater nurses were included in the study. Glove samples were collected from the inner surface of the external glove and from the external surface of the inner glove from operating surgeons wearing a double pair of gloves. Personnel urine samples were collected before, after and 24 h from the procedure. RESULTS: Air and urine samples permanently resulted below detectable levels for cisplatin presence on all the tested sources and sessions. Cisplatin contamination was detected on the inner surface of the external gloves and on the outer surface of the inner gloves, but in a lower concentration for the latter. Skin wipe samples were below detectable levels for platinum presence. CONCLUSION: The results suggest that two pairs of gloves are adequate to protect the skin from antiblastic drugs. No sign of direct contact or systemic absorption of drugs was ever detected from the inspected samples. Semi-closed HIPEC technique appears to be a safe procedure for operators.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Peritoneales / Quimioterapia del Cáncer por Perfusión Regional / Carcinoma / Exposición Profesional / Cisplatino / Personal de Salud / Contaminantes Atmosféricos / Guantes Quirúrgicos / Hipertermia Inducida / Antineoplásicos Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Surg Oncol Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Peritoneales / Quimioterapia del Cáncer por Perfusión Regional / Carcinoma / Exposición Profesional / Cisplatino / Personal de Salud / Contaminantes Atmosféricos / Guantes Quirúrgicos / Hipertermia Inducida / Antineoplásicos Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Surg Oncol Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido