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Aqueous extract of red deer antler promotes hair growth by regulating the hair cycle and cell proliferation in hair follicles.
Li, Jing-jie; Li, Zheng; Gu, Li-juan; Wang, Yun-bo; Lee, Mi-ra; Sung, Chang-keun.
Afiliación
  • Li JJ; Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University, 220 Gung-dong, Yusung-gu, Daejeon 305-764, Republic of Korea.
  • Li Z; Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University, 220 Gung-dong, Yusung-gu, Daejeon 305-764, Republic of Korea.
  • Gu LJ; Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University, 220 Gung-dong, Yusung-gu, Daejeon 305-764, Republic of Korea.
  • Wang YB; Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University, 220 Gung-dong, Yusung-gu, Daejeon 305-764, Republic of Korea.
  • Lee MR; Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University, 220 Gung-dong, Yusung-gu, Daejeon 305-764, Republic of Korea.
  • Sung CK; Department of Food Science and Technology, College of Agriculture and Biotechnology, Chungnam National University, 220 Gung-dong, Yusung-gu, Daejeon 305-764, Republic of Korea.
ScientificWorldJournal ; 2014: 878162, 2014.
Article en En | MEDLINE | ID: mdl-24695964
Deer antlers are the only mammalian appendage capable of regeneration. We aimed to investigate the effect of red deer antler extract in regulating hair growth, using a mouse model. The backs of male mice were shaved at eight weeks of age. Crude aqueous extracts of deer antler were prepared at either 4 °C or 100 °C and injected subcutaneously to two separate groups of mice (n = 9) at 1 mL/day for 10 consecutive days, with water as a vehicle control group. The mice skin quantitative hair growth parameters were measured and 5-bromo-2-deoxyuridine was used to identify label-retaining cells. We found that, in both the 4 °C and the 100 °C deer antler aqueous extract-injection groups, the anagen phase was extended, while the number of BrdU-incorporated cells was dramatically increased. These results indicate that deer antler aqueous extract promotes hair growth by extending the anagen phase and regulating cell proliferation in the hair follicle region.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cuernos de Venado / Productos Biológicos / Folículo Piloso / Proliferación Celular Límite: Animals Idioma: En Revista: ScientificWorldJournal Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cuernos de Venado / Productos Biológicos / Folículo Piloso / Proliferación Celular Límite: Animals Idioma: En Revista: ScientificWorldJournal Asunto de la revista: MEDICINA Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos