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Structure-activity relationship study of 4EGI-1, small molecule eIF4E/eIF4G protein-protein interaction inhibitors.
Takrouri, Khuloud; Chen, Ting; Papadopoulos, Evangelos; Sahoo, Rupam; Kabha, Eihab; Chen, Han; Cantel, Sonia; Wagner, Gerhard; Halperin, Jose A; Aktas, Bertal H; Chorev, Michael.
Afiliación
  • Takrouri K; Laboratory for Translational Research, Hematology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 7, Boston, MA 02115, USA.
  • Chen T; Laboratory for Translational Research, Hematology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 7, Boston, MA 02115, USA.
  • Papadopoulos E; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
  • Sahoo R; Laboratory for Translational Research, Hematology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 7, Boston, MA 02115, USA.
  • Kabha E; Laboratory for Translational Research, Harvard Medical School, USA.
  • Chen H; Laboratory for Translational Research, Harvard Medical School, USA.
  • Cantel S; Laboratory for Translational Research, Harvard Medical School, USA.
  • Wagner G; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
  • Halperin JA; Laboratory for Translational Research, Hematology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 7, Boston, MA 02115, USA.
  • Aktas BH; Laboratory for Translational Research, Hematology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 7, Boston, MA 02115, USA.
  • Chorev M; Laboratory for Translational Research, Hematology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Thorn 7, Boston, MA 02115, USA. Electronic address: michael_chorev@hms.harvard.edu.
Eur J Med Chem ; 77: 361-77, 2014 Apr 22.
Article en En | MEDLINE | ID: mdl-24675136
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazoles / Proteínas de Transporte Nucleocitoplasmático / Factor 4G Eucariótico de Iniciación / Hidrazonas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazoles / Proteínas de Transporte Nucleocitoplasmático / Factor 4G Eucariótico de Iniciación / Hidrazonas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Francia