[Carcinogenicity of antineoplastic drugs: classification, protection and prevention, use and evidence]. / Cancerogenicità dei farmaci antiblastici, classificazioni, protezione e prevenzione, utilizzo ed evidenze.
G Ital Med Lav Ergon
; 36(1): 5-16, 2014.
Article
en It
| MEDLINE
| ID: mdl-24665622
Many antineoplastic agents have been shown to be mutagenic, teratogenic and carcinogenic in experimental studies and secondary malignant neoplasms are known to be associated with several specific therapeutic treatments. However, the occupational exposure to antineoplastic drugs in health care workers has different routes of exposure, dose and duration compared to patients undergoing treatment protocols. The aims of this review are to analyze and to update the National and International Classification, and deepening the topics of occupational exposure, current operating conditions, the technical and operational progress to reducing the exposure, the epidemiological evidence and exposure measurement data available. Finally, we illustrate the dispersion in the environment as a real risk for the general population.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carcinógenos
/
Exposición Profesional
/
Personal de Salud
/
Neoplasias
/
Antineoplásicos
/
Enfermedades Profesionales
Tipo de estudio:
Etiology_studies
/
Guideline
/
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
It
Revista:
G Ital Med Lav Ergon
Asunto de la revista:
MEDICINA OCUPACIONAL
Año:
2014
Tipo del documento:
Article
Pais de publicación:
Italia