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An inactivated oil-emulsion fowl Adenovirus serotype 4 vaccine provides broad cross-protection against various serotypes of fowl Adenovirus.
Kim, Myeong-Seob; Lim, Tae-Hyun; Lee, Dong-Hun; Youn, Ha-Na; Yuk, Seong-Su; Kim, Byoung-Yoon; Choi, Soo-Won; Jung, Cheong-Hwan; Han, Jang-Hyuck; Song, Chang-Seon.
Afiliación
  • Kim MS; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
  • Lim TH; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
  • Lee DH; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
  • Youn HN; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
  • Yuk SS; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
  • Kim BY; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
  • Choi SW; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.
  • Jung CH; KBNP Technology Institute, 254-18, Dugok-Ri, Sinam, Yesan, Republic of Korea.
  • Han JH; KBNP Technology Institute, 254-18, Dugok-Ri, Sinam, Yesan, Republic of Korea.
  • Song CS; Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea. Electronic address: songcs@konkuk.ac.kr.
Vaccine ; 32(28): 3564-8, 2014 Jun 12.
Article en En | MEDLINE | ID: mdl-24662704
The number of clinical cases of inclusion body hepatitis (IBH) and hydropericardium-hepatitis syndrome (HHS) has been increasing, resulting in considerable economic losses in many countries. Currently, only fowl Adenovirus (FAdV) serotype 4 (FAdV-4) has been reported as the causative agent of HHS, whereas IBH can be caused by all 12 serotypes of FAdV. For protection against HHS, various live and killed FAdV serotype 4 vaccines have been developed. However, there is a concern whether these vaccines composed of FAdV-4 alone could provide protection against IBH, which is caused by other serotypes of virulent FAdVs. To date, there have been no reports evaluating the protective efficacy of the FAdV-4 vaccine against other serotypes of FAdV. Thus, we investigated the cross-protection efficacy of an inactivated oil-emulsion FAdV-4 vaccine against various serotypes of FAdV field isolates. Our study demonstrated that the inactivated oil-emulsion FAdV-4 vaccine could provide broad cross-protection against various serotypes of FAdV in not only vaccinated birds, but also the progenies of vaccinated breeder. Therefore, we conclude that the inactivated oil-emulsion FAdV-4 vaccine could be effective in preventing the spread of various other serotypes of FAdV as well as FAdV-4 infection in the poultry industry.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de las Aves de Corral / Vacunas Virales / Infecciones por Adenoviridae / Protección Cruzada Límite: Animals Idioma: En Revista: Vaccine Año: 2014 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de las Aves de Corral / Vacunas Virales / Infecciones por Adenoviridae / Protección Cruzada Límite: Animals Idioma: En Revista: Vaccine Año: 2014 Tipo del documento: Article Pais de publicación: Países Bajos