Your browser doesn't support javascript.
loading
Mechanisms and consequences of injury and repair in older organ transplants.
Slegtenhorst, Bendix R; Dor, Frank J M F; Elkhal, Abdala; Rodriguez, Hector; Yang, Xiaoyong; Edtinger, Karoline; Quante, Markus; Chong, Anita S; Tullius, Stefan G.
Afiliación
  • Slegtenhorst BR; 1 Division of Transplant Surgery and Transplant Surgery Research Laboratory, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. 2 Division of Transplant Surgery, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands. 3 Department of Cardiovascular Surgery, University Hospital of Zurich, Zurich, Switzerland. 4 Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. 5 Department of Surger
Transplantation ; 97(11): 1091-9, 2014 Jun 15.
Article en En | MEDLINE | ID: mdl-24646769
Donor organ scarcity remains a significant clinical challenge in transplantation. Older organs, increasingly utilized to meet the growing demand for donor organs, have been linked to inferior transplant outcomes. Susceptibility to organ injury, reduced repair capacity, and increased immunogenicity are interrelated and impacted by physiological and pathological aging processes. Insights into the underlying mechanisms are needed to develop age-specific interventional strategies with regards to organ preservation, immunosuppression, and allocation. In this overview, we summarize current knowledge of injury and repair mechanisms and the effects of aging relevant to transplantation.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Donantes de Tejidos / Envejecimiento / Trasplante de Órganos Límite: Adult / Aged / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Transplantation Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Donantes de Tejidos / Envejecimiento / Trasplante de Órganos Límite: Adult / Aged / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Transplantation Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos