Clusterin stimulates the chemotactic migration of macrophages through a pertussis toxin sensitive G-protein-coupled receptor and GßÎ³-dependent pathways.

Kang, Byeong-Ho; Shim, Young-Jun; Tae, Yoo-Keung; Song, Jin-A; Choi, Byong-Kwan; Park, In-Sun; Min, Bon-Hong

Kang, Byeong-Ho; Shim, Young-Jun; Tae, Yoo-Keung; Song, Jin-A; Choi, Byong-Kwan; Park, In-Sun; Min, Bon-Hong.

Afiliación

Kang BH; Department of Pharmacology, College of Medicine, Korea University, Seoul, Republic of Korea.
Shim YJ; Department of Pharmacology, College of Medicine, Korea University, Seoul, Republic of Korea.
Tae YK; Department of Pharmacology, College of Medicine, Korea University, Seoul, Republic of Korea.
Song JA; Department of Pharmacology, College of Medicine, Korea University, Seoul, Republic of Korea.
Choi BK; Department of Internal Medicine, College of Medicine, Dongguk University Ilsan Hospital, Republic of Korea.
Park IS; Department of Anatomy, College of Medicine, Inha University, Republic of Korea.
Min BH; Department of Pharmacology, College of Medicine, Korea University, Seoul, Republic of Korea. Electronic address: bhmin@korea.ac.kr.

Biochem Biophys Res Commun ; 445(3): 645-50, 2014 Mar 14.

Article en En | MEDLINE | ID: mdl-24569077

Asunto(s)

Quimiotaxis; Clusterina/metabolismo; Macrófagos/citología; Receptores Acoplados a Proteínas G/metabolismo; Animales; Quimiotaxis/efectos de los fármacos; Humanos; Macrófagos/efectos de los fármacos; Macrófagos/metabolismo; Ratones; Proteínas Quinasas Activadas por Mitógenos/metabolismo; Toxina del Pertussis/farmacología; Fosfatidilinositol 3-Quinasas/metabolismo; Inhibidores de las Quinasa Fosfoinosítidos-3; Transducción de Señal; Fosfolipasas de Tipo C/antagonistas & inhibidores; Fosfolipasas de Tipo C/metabolismo

Palabras clave

Chemotaxis; Clusterin; G-protein-coupled receptor; Macrophage; Pertussis toxin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quimiotaxis / Receptores Acoplados a Proteínas G / Clusterina / Macrófagos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos

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