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Health-related quality of life improves during one year of medical and surgical treatment in a European population-based inception cohort of patients with inflammatory bowel disease--an ECCO-EpiCom study.
Burisch, J; Weimers, P; Pedersen, N; Cukovic-Cavka, S; Vucelic, B; Kaimakliotis, I; Duricova, D; Bortlik, M; Shonová, O; Vind, I; Avnstrøm, S; Thorsgaard, N; Krabbe, S; Andersen, V; Dahlerup, J F; Kjeldsen, J; Salupere, R; Olsen, J; Nielsen, K R; Manninen, P; Collin, P; Katsanos, K H; Tsianos, E V; Ladefoged, K; Lakatos, L; Ragnarsson, G; Björnsson, E; Bailey, Y; O'Morain, C; Schwartz, D; Odes, S; Valpiani, D; Boni, M C; Jonaitis, L; Kupcinskas, L; Turcan, S; Barros, L; Magro, F; Lazar, D; Goldis, A; Nikulina, I; Belousova, E; Fernandez, A; Sanroman, L; Almer, S; Zhulina, Y; Halfvarson, J; Arebi, N; Diggory, T; Sebastian, S.
Afiliación
  • Burisch J; Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark. Electronic address: burisch@dadlnet.dk.
  • Weimers P; Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark.
  • Pedersen N; Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark.
  • Cukovic-Cavka S; Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia.
  • Vucelic B; Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia.
  • Kaimakliotis I; Nicosia Private Practice, Nicosia, Cyprus.
  • Duricova D; IBD Center ISCARE, Charles University, Prague, Czech Republic.
  • Bortlik M; IBD Center ISCARE, Charles University, Prague, Czech Republic.
  • Shonová O; Gastroenterology Department, Hospital Ceské Budejovice, Ceské Budejovice, Czech Republic.
  • Vind I; Department of Medicine, Amager Hospital, Amager, Denmark.
  • Avnstrøm S; Department of Medicine, Amager Hospital, Amager, Denmark.
  • Thorsgaard N; Department of Medicine, Herning Central Hospital, Herning, Denmark.
  • Krabbe S; Medical Department, Viborg Regional Hospital, Viborg, Denmark.
  • Andersen V; Medical Department, Viborg Regional Hospital, Viborg, Denmark; Medical Department, Hospital of Southern Jutland, Aabenraa, Denmark; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
  • Dahlerup JF; Department of Medicine V, Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
  • Kjeldsen J; Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark.
  • Salupere R; Division of Endocrinology and Gastroenterology, Tartu University Hospital, Tartu, Estonia.
  • Olsen J; Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands.
  • Nielsen KR; Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands.
  • Manninen P; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
  • Collin P; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
  • Katsanos KH; 1st Division of Internal Medicine and Division of Gastroenterology, Medical School, University of Ioannina, Ioannina, Greece.
  • Tsianos EV; 1st Division of Internal Medicine and Division of Gastroenterology, Medical School, University of Ioannina, Ioannina, Greece.
  • Ladefoged K; Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland.
  • Lakatos L; Department of Medicine, Csolnoky F. Province Hospital, Veszprem, Hungary.
  • Ragnarsson G; Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland.
  • Björnsson E; Department of Internal Medicine, Section of Gastroenterology and Hepatology, The National University Hospital, Reykjavik, Iceland.
  • Bailey Y; Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland.
  • O'Morain C; Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland.
  • Schwartz D; Department of Gastroenterology and Hepatology, Soroka Medical Center and Ben Gurion University of the Negev, Beer Sheva, Israel; Department of Gastroenterology and Hepatology, Ben Gurion University of the Negev, Beer Sheva, Israel.
  • Odes S; Department of Gastroenterology and Hepatology, Soroka Medical Center and Ben Gurion University of the Negev, Beer Sheva, Israel; Department of Gastroenterology and Hepatology, Ben Gurion University of the Negev, Beer Sheva, Israel.
  • Valpiani D; U.O. Gastroenterologia ed Endoscopia Digestiva, Ospedale Morgagni - Pierantoni, Forlì, Italy; On behalf of the EpiCom Northern Italy centre based in Crema & Cremona, Firenze, Forlì, Padova and Reggio Emilia, Italy.
  • Boni MC; U.O. Medicina 3° e Gastroenterologia, Azienda Ospedaliera Arcispedale S. Maria Nuova, Reggio Emilia, Italy; On behalf of the EpiCom Northern Italy centre based in Crema & Cremona, Firenze, Forlì, Padova and Reggio Emilia, Italy.
  • Jonaitis L; Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania.
  • Kupcinskas L; Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania.
  • Turcan S; Department of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Republic of Moldova.
  • Barros L; Hospital de Vale de Sousa, Porto, Portugal.
  • Magro F; Department of Gastroenterology, Hospital São João, Porto, Portugal; Institute of Pharmacology and Therapeutics, Faculty of Medicine, University of Porto, Porto, Portugal; IBMC - Institute for Molecular and Cell Biology, University of Porto, Porto, Portugal.
  • Lazar D; Clinic of Gastroenterology, University of Medicine 'Victor Babes', Timisoara, Romania.
  • Goldis A; Clinic of Gastroenterology, University of Medicine 'Victor Babes', Timisoara, Romania.
  • Nikulina I; Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russian Federation.
  • Belousova E; Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russian Federation.
  • Fernandez A; Gastroenterology Department, POVISA Hospital, Vigo, Spain.
  • Sanroman L; Gastroenterology Department, Complexo Hospitalario Universitario de Vigo, Vigo, Spain.
  • Almer S; Division of Gastroenterology and Hepatology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Gastroenterology/UHL, County Council of Östergötland, Linköping, Sweden.
  • Zhulina Y; Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden.
  • Halfvarson J; Department of Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden; School of Health and Medical Sciences, Örebro University, Örebro, Sweden.
  • Arebi N; St. Mark's Hospital, Imperial College London, London, UK.
  • Diggory T; Hull and East Yorkshire NHS Trust & Hull and York Medical School, Hull Royal Infirmary, Hull, UK; Hull and York Medical School, Hull Royal Infirmary, Hull, UK.
  • Sebastian S; Hull and East Yorkshire NHS Trust & Hull and York Medical School, Hull Royal Infirmary, Hull, UK; Hull and York Medical School, Hull Royal Infirmary, Hull, UK.
J Crohns Colitis ; 8(9): 1030-42, 2014 Sep.
Article en En | MEDLINE | ID: mdl-24560877
BACKGROUND & AIMS: Health-related quality of life (HRQoL) is impaired in patients with Inflammatory Bowel Disease (IBD). The aim was prospectively to assess and validate the pattern of HRQoL in an unselected, population-based inception cohort of IBD patients from Eastern and Western Europe. METHODS: The EpiCom inception cohort consists of 1560 IBD patients from 31 European centres covering a background population of approximately 10.1 million. Patients answered the disease specific Short Inflammatory Bowel Disease Questionnaire (SIBDQ) and generic Short Form 12 (SF-12) questionnaire at diagnosis and after one year of follow-up. RESULTS: In total, 1079 patients were included in this study. Crohn's disease (CD) patients mean SIBDQ scores improved from 45.3 to 55.3 in Eastern Europe and from 44.9 to 53.6 in Western Europe. SIBDQ scores for ulcerative colitis (UC) patients improved from 44.9 to 57.4 and from 48.8 to 55.7, respectively. UC patients needing surgery or biologicals had lower SIBDQ scores before and after compared to the rest, while biological therapy improved SIBDQ scores in CD. CD and UC patients in both regions improved all SF-12 scores. Only Eastern European UC patients achieved SF-12 summary scores equal to or above the normal population. CONCLUSION: Medical and surgical treatment improved HRQoL during the first year of disease. The majority of IBD patients in both Eastern and Western Europe reported a positive perception of disease-specific but not generic HRQoL. Biological therapy improved HRQoL in CD patients, while UC patients in need of surgery or biological therapy experienced lower perceptions of HRQoL than the rest.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Procedimientos Quirúrgicos del Sistema Digestivo / Enfermedades Inflamatorias del Intestino / Vigilancia de la Población / Manejo de la Enfermedad Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspecto: Patient_preference Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Crohns Colitis Asunto de la revista: GASTROENTEROLOGIA Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Procedimientos Quirúrgicos del Sistema Digestivo / Enfermedades Inflamatorias del Intestino / Vigilancia de la Población / Manejo de la Enfermedad Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspecto: Patient_preference Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Crohns Colitis Asunto de la revista: GASTROENTEROLOGIA Año: 2014 Tipo del documento: Article Pais de publicación: Reino Unido