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Chronic migraine with and without medication overuse: experience in a hospital series of 434 patients.
Rojo, E; Pedraza, M I; Muñoz, I; Mulero, P; Ruiz, M; de la Cruz, C; Barón, J; Rodríguez, C; Herrero, S; Guerrero, A L.
Afiliación
  • Rojo E; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. Electronic address: erojo80@yahoo.it.
  • Pedraza MI; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Muñoz I; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Mulero P; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Ruiz M; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • de la Cruz C; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Barón J; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Rodríguez C; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Herrero S; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Guerrero AL; Servicio de Neurología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Neurologia ; 30(3): 153-7, 2015 Apr.
Article en En, Es | MEDLINE | ID: mdl-24468658
INTRODUCTION: Chronic migraine (CM) is a complication of episodic migraine, favored by risk factors as medication overuse (MO). We intend to compare demographic and clinic characteristics of a series of CM patients, with and without MO. METHODS: The study included patients with CM (2006 revised criteria) attended in a headache outpatient office located in a tertiary hospital between January 2008 and May 2012. We recorded demographic characteristics, age at migraine onset, time from onset, previous use of symptomatic or preventive therapy, and headache impact measured with six-item headache impact test (HIT-6). RESULTS: A total of 434 patients (357 women, 77 men) were diagnosed with CM out of the 1868 (23.2%) that attended our clinic. Of these, 258 (72.2%) fulfilled criteria of MO, and 59.8% of those with MO, and 41.1% of cases without MO had previously received preventative treatment (P<.001). Age at onset of migraine was lower in MO patients (21.2±10.1 vs 23.8±12.5 years, P=.02) and time from onset to headache clinic consultation was higher in MO cases (23.8±14.1 vs 18.3±14.8 years, P<.001). We found no difference between both groups in average HIT-6 score and the percentage of patients with a HIT-6 score over 55. CONCLUSIONS: CM, with or without MO, is a burdensome group of patients in our headache clinic. Patients with MO are referred later and have more frequently received preventive treatments.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Uso Excesivo de Medicamentos Recetados / Trastornos Migrañosos Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Neurologia Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: España
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Uso Excesivo de Medicamentos Recetados / Trastornos Migrañosos Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Neurologia Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article Pais de publicación: España