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Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.
Kim, Hyung-Jun; Raphael, Alya R; LaDow, Eva S; McGurk, Leeanne; Weber, Ross A; Trojanowski, John Q; Lee, Virginia M-Y; Finkbeiner, Steven; Gitler, Aaron D; Bonini, Nancy M.
Afiliación
  • Kim HJ; 1] Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA. [2].
  • Raphael AR; Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.
  • LaDow ES; Gladstone Institute of Neurological Disease, San Francisco, California, USA.
  • McGurk L; Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Weber RA; Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Trojanowski JQ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Lee VM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Finkbeiner S; Gladstone Institute of Neurological Disease, San Francisco, California, USA.
  • Gitler AD; Department of Genetics, Stanford University School of Medicine, Stanford, California, USA.
  • Bonini NM; Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Nat Genet ; 46(2): 152-60, 2014 Feb.
Article en En | MEDLINE | ID: mdl-24336168
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenina / Factor 2 Eucariótico de Iniciación / Proteínas de Unión al ADN / Esclerosis Amiotrófica Lateral / Indoles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenina / Factor 2 Eucariótico de Iniciación / Proteínas de Unión al ADN / Esclerosis Amiotrófica Lateral / Indoles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos