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Bedside to bench: The risk of bleeding with parenteral omega-3 lipid emulsion therapy.
Dicken, Bryan J; Bruce, Aisha; Samuel, Tarah M; Wales, Paul W; Nahirniak, Susan; Turner, Justine M.
Afiliación
  • Dicken BJ; Pediatric General Surgery, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada. Electronic address: bdicken@ualberta.ca.
  • Bruce A; Pediatric Hematology and Oncology, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
  • Samuel TM; Pediatric Gastroenterology, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada.
  • Wales PW; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Pediatric General Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
  • Nahirniak S; Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada.
  • Turner JM; Pediatric Gastroenterology, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Department of Agriculture, Life and Environmental Sciences, University of Alberta, Edmonton, Alberta, Canada.
J Pediatr ; 164(3): 652-4, 2014 Mar.
Article en En | MEDLINE | ID: mdl-24321533
Our clinical experience led us to reassess the effect of sole omega-3 lipid therapy on hemostasis. We compared thromboelastography platelet mapping in neonatal piglets given sole omega-3 lipid. We identified abnormalities in reaction time (P = .025) and the arachidonic acid pathway (P = .025). The potential for bleeding complications from parenteral omega-3 lipid emulsion therapy in high-risk infants with liver disease has been dismissed but, on the basis of this data, should be reconsidered.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceites de Pescado / Nutrición Parenteral / Emulsiones Grasas Intravenosas / Hemorragia Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Infant / Male Idioma: En Revista: J Pediatr Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceites de Pescado / Nutrición Parenteral / Emulsiones Grasas Intravenosas / Hemorragia Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Infant / Male Idioma: En Revista: J Pediatr Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos