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CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells.
Delehouzé, C; Godl, K; Loaëc, N; Bruyère, C; Desban, N; Oumata, N; Galons, H; Roumeliotis, T I; Giannopoulou, E G; Grenet, J; Twitchell, D; Lahti, J; Mouchet, N; Galibert, M-D; Garbis, S D; Meijer, L.
Afiliación
  • Delehouzé C; ManRos Therapeutics, Hôtel de Recherche, Centre de Perharidy, Roscoff, France.
  • Godl K; Evotec (München) GmbH, Am Klopferspitz 19a, Martinsried, Germany.
  • Loaëc N; 1] ManRos Therapeutics, Hôtel de Recherche, Centre de Perharidy, Roscoff, France [2] C.N.R.S., 'Protein Phosphorylation & Human Disease' Group, Station Biologique, B.P. 74, Roscoff cedex, Bretagne, France.
  • Bruyère C; ManRos Therapeutics, Hôtel de Recherche, Centre de Perharidy, Roscoff, France.
  • Desban N; C.N.R.S., 'Protein Phosphorylation & Human Disease' Group, Station Biologique, B.P. 74, Roscoff cedex, Bretagne, France.
  • Oumata N; ManRos Therapeutics, Hôtel de Recherche, Centre de Perharidy, Roscoff, France.
  • Galons H; Laboratoire de Chimie Organique 2, INSERM U 648, Université Paris-Descartes, 4 avenue de l'Observatoire, Paris cedex, France.
  • Roumeliotis TI; Cancer Sciences & Clinical and Experimental Medicine, University of Southampton, Institute for Life Sciences, Center for Proteomics & Metabolomics Research, Highfield Campus, Southampton, UK.
  • Giannopoulou EG; Institute for Computational Biomedicine, Weil Cornell Medical College, New York, NY, USA.
  • Grenet J; Department of Tumor Cell Biology, St Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN, USA.
  • Twitchell D; Department of Tumor Cell Biology, St Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN, USA.
  • Lahti J; Department of Tumor Cell Biology, St Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN, USA.
  • Mouchet N; CNRS UMR 6290-Institut de Génétique et Développement de Rennes, Equipe Expression des Gènes et Oncogenèse, Université de Rennes1, SFR Biosit, Faculté de Médecine, 2 avenue du Pr. Léon Bernard, Rennes cedex, France.
  • Galibert MD; CNRS UMR 6290-Institut de Génétique et Développement de Rennes, Equipe Expression des Gènes et Oncogenèse, Université de Rennes1, SFR Biosit, Faculté de Médecine, 2 avenue du Pr. Léon Bernard, Rennes cedex, France.
  • Garbis SD; Cancer Sciences & Clinical and Experimental Medicine, University of Southampton, Institute for Life Sciences, Center for Proteomics & Metabolomics Research, Highfield Campus, Southampton, UK.
  • Meijer L; 1] ManRos Therapeutics, Hôtel de Recherche, Centre de Perharidy, Roscoff, France [2] C.N.R.S., 'Protein Phosphorylation & Human Disease' Group, Station Biologique, B.P. 74, Roscoff cedex, Bretagne, France.
Oncogene ; 33(50): 5675-87, 2014 Dec 11.
Article en En | MEDLINE | ID: mdl-24317512
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Purinas / Piridinas / Proteínas Nucleares / Proteínas Oncogénicas / Inhibidores de Proteínas Quinasas / Neuroblastoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Purinas / Piridinas / Proteínas Nucleares / Proteínas Oncogénicas / Inhibidores de Proteínas Quinasas / Neuroblastoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido