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Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: role of Asn181 and Ile335 validated by spectroscopic and computational studies.
Juárez-Jiménez, Jordi; Mendes, Eduarda; Galdeano, Carles; Martins, Carla; Silva, Daniel B; Marco-Contelles, José; do Carmo Carreiras, Maria; Luque, F Javier; Ramsay, Rona R.
Afiliación
  • Juárez-Jiménez J; Department of Physical Chemistry, Faculty of Pharmacy and Institute of Biomedicine (IBUB), University of Barcelona, Avda. Prat de la Riba 171, 08921 Santa Coloma de Gramenet, Spain.
  • Mendes E; iMed.UL - Research Institute for Medicines and Pharmaceutical Sciences, Faculty of Pharmacy, University of Lisbon, Avda. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
  • Galdeano C; Department of Physical Chemistry, Faculty of Pharmacy and Institute of Biomedicine (IBUB), University of Barcelona, Avda. Prat de la Riba 171, 08921 Santa Coloma de Gramenet, Spain.
  • Martins C; iMed.UL - Research Institute for Medicines and Pharmaceutical Sciences, Faculty of Pharmacy, University of Lisbon, Avda. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
  • Silva DB; iMed.UL - Research Institute for Medicines and Pharmaceutical Sciences, Faculty of Pharmacy, University of Lisbon, Avda. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
  • Marco-Contelles J; Laboratorio de Radicales Libres y Química Computacional, Instituto de Química Orgánica General, Consejo Superior de Investigaciones Científicas, c/. Juan de la Cierva 3, 28006 Madrid, Spain.
  • do Carmo Carreiras M; iMed.UL - Research Institute for Medicines and Pharmaceutical Sciences, Faculty of Pharmacy, University of Lisbon, Avda. Prof. Gama Pinto, 1649-003 Lisbon, Portugal.
  • Luque FJ; Department of Physical Chemistry, Faculty of Pharmacy and Institute of Biomedicine (IBUB), University of Barcelona, Avda. Prat de la Riba 171, 08921 Santa Coloma de Gramenet, Spain.
  • Ramsay RR; School of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews KY16 9ST, UK. Electronic address: rrr@st-andrews.ac.uk.
Biochim Biophys Acta ; 1844(2): 389-97, 2014 Feb.
Article en En | MEDLINE | ID: mdl-24247011
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asparagina / Furanos / Isoleucina / Monoaminooxidasa / Inhibidores de la Monoaminooxidasa Límite: Humans Idioma: En Revista: Biochim Biophys Acta Año: 2014 Tipo del documento: Article País de afiliación: España Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asparagina / Furanos / Isoleucina / Monoaminooxidasa / Inhibidores de la Monoaminooxidasa Límite: Humans Idioma: En Revista: Biochim Biophys Acta Año: 2014 Tipo del documento: Article País de afiliación: España Pais de publicación: Países Bajos