[Approaches to the control of lymphogenic metastatic spread of tumors]. / Puti vozdeistviia na limfogennoe metastazirovanie opukholi.
Vopr Onkol
; 32(4): 62-5, 1986.
Article
en Ru
| MEDLINE
| ID: mdl-2422815
Lymphopoiesis stimulating drugs were injected into the blood of rabbits bearing Brown-Pearce transplantable tumor. It was found that treatment with mannitol targeted on osmoregulation mechanisms and terrilytin--on blood and lymph coagulation intensified the lymphogenic migration of tumor cells. When used in an experimental series involving endolymphic transplantation of tumor cells, the said drugs promoted tumor cell passage from lymph to blood, which resulted in an increased number of metastasis-bearing animals. It was also found that the promoting effect may be counteracted by preliminary endolymphic injection of a fat-soluble antitumor preparation. Lymphopoiesis and lymph flow stimulation in conjunction with thoracic duct draining may be used for removal of tumor cells from the lymphatics.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Brown-Pearce
/
Metástasis Linfática
/
Sistema Linfático
Límite:
Animals
Idioma:
Ru
Revista:
Vopr Onkol
Año:
1986
Tipo del documento:
Article
Pais de publicación:
Rusia