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The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).
Ciarapica, R; De Salvo, M; Carcarino, E; Bracaglia, G; Adesso, L; Leoncini, P P; Dall'Agnese, A; Walters, Z S; Verginelli, F; De Sio, L; Boldrini, R; Inserra, A; Bisogno, G; Rosolen, A; Alaggio, R; Ferrari, A; Collini, P; Locatelli, M; Stifani, S; Screpanti, I; Rutella, S; Yu, Q; Marquez, V E; Shipley, J; Valente, S; Mai, A; Miele, L; Puri, P L; Locatelli, F; Palacios, D; Rota, R.
Afiliación
  • Ciarapica R; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • De Salvo M; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Carcarino E; IRCCS Fondazione Santa Lucia, Roma, Italy.
  • Bracaglia G; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Adesso L; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Leoncini PP; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Dall'Agnese A; IRCCS Fondazione Santa Lucia, Roma, Italy.
  • Walters ZS; Sarcoma Molecular Pathology, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, UK.
  • Verginelli F; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • De Sio L; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Boldrini R; Department of Pathology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Inserra A; Department of Surgery, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Bisogno G; Department of Pediatrics, Oncohematology Unit, University of Padova, Padova, Italy.
  • Rosolen A; Department of Pediatrics, Oncohematology Unit, University of Padova, Padova, Italy.
  • Alaggio R; Medicine DIMED, Pathology Unit, University of Padova, Padova, Italy.
  • Ferrari A; Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
  • Collini P; Anatomic Pathology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
  • Locatelli M; Scientific Directorate, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Stifani S; Centre for Neuronal Survival, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
  • Screpanti I; Department of Molecular Medicine, Sapienza University, Roma, Italy.
  • Rutella S; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
  • Yu Q; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.
  • Marquez VE; Chemical Biology Laboratory, Frederick National Laboratory for Cancer Research, CCR, National Cancer Institute, NIH, Frederick, MD, USA.
  • Shipley J; Sarcoma Molecular Pathology, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, UK.
  • Valente S; Istituto Pasteur, Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University, Roma, Italy.
  • Mai A; Istituto Pasteur, Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University, Roma, Italy.
  • Miele L; Cancer Institute, University of Mississippi Medical Center, Jackson, MS, USA.
  • Puri PL; 1] IRCCS Fondazione Santa Lucia, Roma, Italy [2] Muscle Development and Regeneration Program, Sanford-Burnham Medical Research Institute, La Jolla, CA, USA.
  • Locatelli F; 1] Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy [2] Dipartimento di Scienze Pediatriche, Università di Pavia, Pavia, Italy.
  • Palacios D; IRCCS Fondazione Santa Lucia, Roma, Italy.
  • Rota R; Department of Oncohematology, Ospedale Pediatrico Bambino Gesù, IRCCS, Roma, Italy.
Oncogene ; 33(32): 4173-84, 2014 Aug 07.
Article en En | MEDLINE | ID: mdl-24213577
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rabdomiosarcoma Alveolar / Proteínas Ligasas SKP Cullina F-box / Factores de Transcripción Paired Box / Factores de Transcripción Forkhead / Complejo Represivo Polycomb 2 / Proteínas Musculares Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rabdomiosarcoma Alveolar / Proteínas Ligasas SKP Cullina F-box / Factores de Transcripción Paired Box / Factores de Transcripción Forkhead / Complejo Represivo Polycomb 2 / Proteínas Musculares Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido