Hypericum perforatum L. preparations for menopause: a meta-analysis of efficacy and safety.
Climacteric
; 17(4): 325-35, 2014 Aug.
Article
en En
| MEDLINE
| ID: mdl-24188229
OBJECTIVE: To compare by meta-analysis the efficacy and adverse events of Hypericum perforatum L. (St. John's Wort), or its combinations, and placebo for menopausal women. DESIGN: A systematic review and meta-analysis were carried out by searching in Pubmed, Cochrane Library, Embase and the Web of Science database. RESULTS: Extracts of Hypericum perforatum L. and its combination with herbs were significantly superior to placebo (standard mean difference = -1.08; 95% confidence interval -1.38 to -0.77); extracts of Hypericum perforatum L. proved to be more effective than placebo in the treatment of menopause. Adverse events occurred in 53 (17.4%) patients on Hypericum perforatum L. preparations and 45 (15.4%) patients on placebo (relative risk = 1.16; 95% confidence interval 0.81-1.66). CONCLUSION: Extracts of Hypericum perforatum L. have possibly fewer side-effects than placebo for the treatment of menopausal women.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Menopausia
/
Sofocos
/
Hypericum
/
Depresión
/
Fitoterapia
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Systematic_reviews
Límite:
Adult
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Female
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Humans
/
Middle aged
Idioma:
En
Revista:
Climacteric
Asunto de la revista:
GINECOLOGIA
Año:
2014
Tipo del documento:
Article
Pais de publicación:
Reino Unido