Sertoli-Leydig cell tumor of the ovary with alpha-fetoprotein production.
Arch Pathol Lab Med
; 110(1): 65-8, 1986 Jan.
Article
en En
| MEDLINE
| ID: mdl-2416299
A case of poorly differentiated Sertoli-Leydig cell tumor with elevated serum alpha-fetoprotein (AFP) levels occurred in a 17-year-old girl. No germ cell component and no heterologous elements were identified, but a retiform pattern was present. Immunohistochemical studies demonstrated immunoreactivity for AFP and testosterone in Leydig's cells only. Secretion of AFP by Sertoli-Leydig cell tumors has rarely been mentioned previously, and its mechanism is difficult to explain. Non-germ cell tumors must be considered in the differential diagnosis of ovarian tumors with elevated serum AFP levels.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
/
Tumor de Células de Sertoli
/
Alfa-Fetoproteínas
/
Tumor de Células de Leydig
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Arch Pathol Lab Med
Año:
1986
Tipo del documento:
Article
Pais de publicación:
Estados Unidos