Antithyroid drug-induced agranulocytosis complicated by pneumococcal sepsis and upper airway obstruction.
Intern Med
; 52(20): 2355-9, 2013.
Article
en En
| MEDLINE
| ID: mdl-24126400
Streptococcus pneumoniae is a rare pathogen of sepsis in patients with antithyroid drug-induced agranulocytosis. We herein describe a case of antithyroid drug-induced agranulocytosis complicated by pneumococcal sepsis and upper airway obstruction. A 27-year-old woman who was previously prescribed methimazole for nine months presented with a four-day history of a sore throat. She nearly choked and was diagnosed with febrile agranulocytosis. She was successfully treated with intubation, intravenous antibiotics and granulocyte colony-stimulating factor. Her blood cultures yielded S. pneumoniae. Emergency airway management, treatment of sepsis and the administration of granulocyte colony-stimulating factor can improve the clinical course of antithyroid drug-induced pneumococcal sepsis in patients with airway obstruction.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones Neumocócicas
/
Antitiroideos
/
Sepsis
/
Agranulocitosis
/
Obstrucción de las Vías Aéreas
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Japón