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Reducing radiation dose while maintaining diagnostic image quality of cerebral three-dimensional digital subtraction angiography: an in vivo study in swine.
Pearl, Monica S; Torok, Collin M; Messina, Steven A; Radvany, Martin; Rao, Swati N; Ehtiati, Tina; Thompson, Carol B; Gailloud, Philippe.
Afiliación
  • Pearl MS; Division of Interventional Neuroradiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Torok CM; Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Messina SA; Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Radvany M; Division of Interventional Neuroradiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Rao SN; Siemens Corporate Research, Baltimore, Maryland, USA.
  • Ehtiati T; Siemens Corporate Research, Baltimore, Maryland, USA.
  • Thompson CB; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Gailloud P; Division of Interventional Neuroradiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Neurointerv Surg ; 6(9): 672-6, 2014 Nov.
Article en En | MEDLINE | ID: mdl-24122004
BACKGROUND: Three-dimensional digital subtraction angiography (3D-DSA) is a modern technique that allows for better appreciation of complex vascular lesions. This study evaluates the impact of various dose reduction strategies on 3D-DSA image quality. METHODS: The standard manufacturer 5 s 0.36 µGy/frame setting was modified to create lower dose 3D-DSA protocols by varying the acquisition time (5 or 3 s) and/or dose per frame (0.36, 0.24, 0.17, and 0.10 µGy/f). All protocols were evaluated in three swine. Four raters measured a segment of the external carotid artery on two-dimensional multiplanar reconstruction images. The raters were also presented with three-dimensional volume rendered images from all protocols in a blinded manner and asked to choose the superior image. A full model analysis of variance with repeated measure factors was performed to compare mean differences in measurements between protocols. RESULTS: Measurement differences between the standard and low dose protocols were not clinically significant (<0.5 mm). All raters demonstrated high inter-rater reliability. The 5 s protocols were considered as qualitatively superior to the 3 s protocols. Delivered system doses ranged from 43.8 to 6.5 mGy. The 5 s 0.10 µGy/frame protocols generated 65-68% less delivered dose compared with the 5 s 0.36 µGy/frame setting. CONCLUSIONS: Low dose 3D-DSA protocols with preserved image quality are achievable, and can help reduce unnecessary radiation exposure to both patients and operators. The 5 s low dose protocols generated clinically acceptable and superior images compared with the 3 s protocols, suggesting a more important role for acquisition time than dose per frame to maintain image quality.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Angiografía de Substracción Digital Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies Límite: Animals Idioma: En Revista: J Neurointerv Surg Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Angiografía de Substracción Digital Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies Límite: Animals Idioma: En Revista: J Neurointerv Surg Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido